Advanced Cancer Therapeutics

Nyhet

Strategies and Technologies for Targeted Drug Delivery

Häftad, Engelska, 2026

Av Manish Kumar, Abhishek Jha, Brahmeshwar Mishra

2 559 kr

Kommande

Advanced Drug Delivery Systems for Targeted Cancer Therapy explores the heterogeneity of tumors and microenvironmental factors that influence cancer treatment and contribute to drug resistance. It discusses critical elements such as tumor stroma, vasculature, pH, hypoxia, and enzymatic activity that impact therapeutic efficacy. The book covers advanced drug formulations, including supramolecular systems, metal-organic frameworks, and nanomedicine, focusing on their roles in selective drug delivery for early detection, diagnosis, and treatment of various cancers. It reviews the current status and future perspectives of these formulations, highlighting their potential to enhance therapeutic outcomes while minimizing side effects. Additionally, it examines the limitations of nanocarriers and addresses regulatory and ethical considerations related to anticancer formulations. This resource is invaluable for researchers, clinicians, and students, offering insights into the latest advancements in drug delivery systems. It bridges the gap between conventional and innovative therapies, equipping the audience with essential knowledge for developing precise cancer treatment strategies.

Presents an extensive examination of various advanced drug formulations, including nanomedicine, supramolecular systems, and metal-organic frameworks, highlighting their roles in targeted cancer therapy
Emphasizes the significance of the tumor microenvironment and heterogeneity in influencing drug resistance, providing insights into how these factors affect therapeutic efficacy and treatment outcomes
Analyzes the limitations of current drug delivery systems, discusses regulatory considerations, and explores future perspectives in anticancer drug delivery

Produktinformation

Utgivningsdatum2026-05-01
Mått191 x 235 x undefined mm
Vikt450 g
FormatHäftad
SpråkEngelska
Antal sidor330
FörlagElsevier Science
ISBN9780443441851

Tillhör följande kategorier

Tillverkningsindustri inom Ekonomi och ledarskap
Farmakologi inom Medicin

Manish Kumar holds the position of Assistant Professor at Amity Institute of Pharmacy in the Greater Noida Campus of Amity University. He completed his doctoral degree at the Indian Institute of Technology (Banaras Hindu University), Varanasi-221005, India. He possesses over 8 years of academic research experience. His research interests are controlled drug delivery systems, nanoemulsions, polymeric nanoparticles, lipid nanoparticles, nanocrystals, nanofibrous scaffolds, hydrogel, and microneedles for treating cancer, wounds, and inflammatory diseases. To date, he has authored over 40 peer-reviewed articles and more than 25 book chapters that have been published in well-known international journals Abhishek Jha is an Assistant Professor at the Department of Pharmaceutics, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pune, Maharashtra. He did his Ph.D. and M.Pharm from the Indian Institute of Technology (Banaras Hindu University), India. He has more than 8 years of professional experience in academic research. His field of research includes the development of novel drug delivery technologies for controlled, targeted, and localized delivery of therapeutics for various ailments, including but not limited to cancer, wounds, and inflammatory diseases. So far he has contributed in more than dozens of peer-reviewed articles and more than 25 book chapters published in reputed international journals.Dr. Brahmeshwar Mishra is a Professor of Pharmaceutics at the Indian Institute of Technology (BHU) in Varanasi, with over 40 years of experience in teaching and research. He has served as the Chairman of the Medical Board at IIT (BHU) from June 2012 to 2023. His expertise lies in the formulation of controlled and novel drug delivery systems, including nanoformulations, focusing on bioavailability and pharmacokinetics. He has supervised over 30 doctoral candidates and nearly 100 postgraduate students, publishing around 300 articles, 226 abstracts, 43 book chapters, and holding 3 patents.He is a leading researcher in drug delivery. He has received numerous awards, including the Best Young Pharmacy Teacher Award and the Pharmacy Excellence Award. Additionally, he has served on editorial boards, traveled internationally for talks, and participated in various academic committees and programs.

I. UNDERSTANDING THE CANCER1. Introduction to cancer2. Current practices in cancer chemotherapy3. Emerging trend in anticancer drug delivery4. Cancer therapy depending on tumor stroma5. Cancer therapy depending on cancer cell respiration: pH and hypoxia6. Cancer therapy depending on tumor vasculature and EPR effects.7. Cancer therapy based on extracellular matrix8. Heterogenicity of cancer and drug resistanceII. STRATEGIES AND TECHNOLOGIES FOR CANCER THERAPY9. Materials and strategies for advanced anticancer drug delivery10. Drug Conjugates for anticancer drug delivery11. Microparticles for anticancer drug delivery12. Self-assembled supramolecular systems for anticancer drug delivery13. Advances in metal-organic frameworks for anticancer drug delivery14. Nanotechnology for anticancer drug delivery: possibilities and limitations15. Tumor microenvironment targeted drug delivery systems16. Advances in dendrimers for anticancer drug delivery17. Advances in metallic nanoparticles for anticancer drug delivery18. Advances in polymeric nanoparticles for anticancer drug delivery19. Advances in lipid-based nanoparticles for anticancer drug delivery20. Advances in SNEDDS for anticancer drug delivery21. Advances in nanocrystals for anticancer drug delivery22. Theranostic nanoparticles for advanced cancer therapy23. Advances in hydrogel for anticancer drug delivery24. Nanofibrous scaffolds for cancer management25. Genetic nanomaterials for anticancer drug delivery26. Organic nanocarriers for anticancer drug delivery27. Microneedles for anticancer drug delivery28. Implants for anticancer drug delivery29. Phytoconstituents based anticancer drug delivery systemsIII. CLINICAL STATUS, CHALLENGES AND FUTURE PROSPECTIVES30. Clinical status of anticancer drug delivery systems31. Challenges and future prospectives in anticancer drug delivery32. Regulatory considerations for anticancer drug delivery systems