Del i serien Cancer Treatment and Research

Adjuvant Therapy of Breast Cancer

Inbunden, Engelska, 1992

2 859 kr

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The results of randomized trials evaluating the use of early adjuvant systematic treatment for patients with respectable breast cancer provide a rebuttal to those who would argue that little progress has been made in the treatment of cancer. Few subjects have been so systematically studied in the history of medicine and it seems fair to conclude that the value of adjuvant systemic therapy in prolonging the lives of women with breast cancer is more firmly supported by empirical evidence than even the more conventional of primary treatments using various combinations of surgery and radiotherapy. This book reviews the rationale for, results of, special problems and future directions of adjuvant therapy of breast cancer. It also includes an appendix from the Early Breast Cancer Trialists' Collaborative Group (OXford) which lists all of the adjuvant trials which have been closed, as well as the active studies now ongoing.

Produktinformation

Utgivningsdatum1992-08-31
Mått155 x 235 x 32 mm
Vikt885 g
FormatInbunden
SpråkEngelska
SerieCancer Treatment and Research
Antal sidor464
Upplaga1992
FörlagKluwer Academic Publishers
ISBN9780792316565

Tillhör följande kategorier

Onkologi inom Medicin

I. Rationale and Methods for Studying Adjuvant Systemic Therapy.- 1. Evolving concepts in the adjuvant systemic therapy of operable breast cancer.- 2. Statistical methods for early breast cancer trials.- II. Results of Clinical Studies.- 3. The nature of the benefit.- 4. Adjuvant endocrine therapy of breast cancer.- 5. Adjuvant chemotherapy of axillary lymph-node-positive breast cancer.- 6. The node-negative problem: To treat or not to treat.- III. Special Problems.- 7. Defining the high-risk breast cancer patient.- 8. Models for weighing benefits and toxicities.- 9. Financial considerations in the use of adjuvant chemotherapy.- 10. The use of adjuvant therapy in patients treated with conservative surgery and radiotherapy.- 11. Treating the relapsed patient.- IV. Future Directions.- 12. Unanswered questions in the adjuvant therapy of breast cancer.- 13. Neoadjuvant chemotherapy.- 14. Altering cell kinetics with endocrine therapy.- 15. Polypeptide growth factors: Their potential value in the management of breast cancer patients.- 16. Immunotherapy of breast cancer.- 17. Breast cancer chemoprevention.- Appendices.- I. Consensus statements from panels convened by The National Cancer Institute in 1980, 1985, 1990.- II. List of completed and ongoing randomized clinical trials addressing questions related to the use of adjuvant systemic therapy to treat resectable breast cancer.

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