A Means to an End

The biological basis of aging and death

Häftad, Engelska, 2002

439 kr

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This book covers ageing from a fundamental cell biological perspective. The evolution and developmental genetics of senescence are explained clearly. All the various theories of ageing -- the Hayflick limit and telomeric shortening as a possible biological clock, the impacts of somatic mutations, oxidative stress, accumulation of waste materials in cells with age -- are explained and critically assessed. The author presents vivid case accounts about disorders that open windows on to the ageing process. The impacts of ageing on the brain and nervous system are given special attention, as are the effects of caloric restriction on maximum lifespan.

Produktinformation

Utgivningsdatum2002-04-25
Mått152 x 231 x 15 mm
Vikt372 g
FormatHäftad
SpråkEngelska
Antal sidor256
FörlagOUP USA
ISBN9780195153750

Tillhör följande kategorier

Geriatrik inom Medicin
Biovetenskap inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik
Populärvetenskap inom Naturvetenskap och teknik

INTRODUCTION ; 1. Aging, Senescence, and Lifespan ; 2. The Nature of Cellular Senescence and Death ; 3. The Evolution of Senescence and Death ; 4. Of Embryos and Worms and Very Old Men: The Developmental Genetics of Senescence and Lifespan ; 5. Human Genetic Diseases that Mimic the Aging Process ; 6. Cycling to Senescence ; 7. Replicative Immortality: Cancer and Aging ; 8. Caloric Restriction and Maximum Lifespan ; 9. With Every Breath We Take: Oxidative Stress and Cellular Senescence ; 10. The Aging Brain ; 11. A Conditional Benefit