50 Landmark Papers every Neurosurgeon Should Know

Dr. Jignesh Tailor is currently Assistant Professor of Neurological Surgery at Indiana University School of Medicine and a Pediatric Neurosurgeon at Riley Hospital for Children. He received his medical degree from the University of Oxford Medical School and holds a PhD in Stem Cell Biology from the University of Cambridge. During neurosurgery training in London, Tailor received a highly competitive Wellcome Trust Post-Doctoral Research Award that allowed him to complete neurosurgery training at the Hospital for Sick Childrenin Toronto, Ontario while doing an enfolded Postdoctoral Research Fellowship at the University of Toronto. He completed fellowship training in Pediatric Neurosurgery at Johns Hopkins University Hospital in Baltimore in July 2021.

• Section One - Tumour1 - Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma2 - MGMT gene silencing and benefit from temozolomide in glioblastoma3 - Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial4 - A randomized trial of surgery in the treatment of single metastases to the brain5 - Prognostic factors for survival in adult patients with cerebral low-grade glioma6 - Long-term outcomes after supratotal resection of diffuse low-grade gliomas: a consecutive series with 11-year follow-up7 - The recurrence of intracranial meningiomas after surgical treatment8 - Phase I/II study of resection and intraoperative cesium-131 radioisotope brachytherapy in patients with newly diagnosed brain metastases9 - Natural history of asymptomatic colloid cysts of the third ventricleSection Two - Vascular 10 - Surgical Risk as Related to Time of Intervention in the Repair of Intracranial Aneurysms11 - International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial12 - International Study of Unruptured Intracranial Aneurysms Investigators. (ISUIA2) Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment.13 - Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial14 - A proposed grading system for arteriovenous malformations15 - Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials16 - Benefit of Carotid Endarterectomy in Patients with Symptomatic Moderate or Severe Stenosis. North American Symptomatic Carotid Endarterectomy Trial (NASCET)17 - Trial of Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH)Section Three - Paediatrics18 - Randomized trial of cerebrospinal fluid shunt valve design in pediatric hydrocephalus. 19 - Endoscopic third ventriculostomy in the treatment of childhood hydrocephalus20 - Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation21 - A Randomized Trial of Prenatal versus Postnatal Repair of Myelomeningocele (MOMS trial)22 - Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants less than 1,500 gm.23 - Intrinsic brain-stem tumors of childhood: surgical indications24 - Molecular subgroups of medulloblastoma: the current consensus25 - Pial Synangiosis for Moyamoya Syndrome in Children26 - Hypothermia Therapy after Traumatic Brain Injury in ChildrenSection Four - Functional/Epilepsy 27 - The first clinical trial to establish deep brain stimulation of the subthalamic nucleus as an evidence-based treatment for Parkinson’s disease28 - The Long-term Outcome of Microvascular Decompression for Trigeminal Neuralgia29 - A Randomized, Controlled Trial of Surgery for Temporal-Lobe Epilepsy30 - Early Identification of Refractory Epilepsy31 - Vagus nerve stimulation for treatment of partial seizures: 1. A controlled study of effect on seizures32 - Intracarotid injection of sodium amytal for the lateralization of cerebral speech dominanceSection Five - Head Trauma 33 - Assessment of coma and impaired consciousness. A practical scale34 - Traumatic Acute Subdural Hematoma: Major Mortality Reduction in Comatose Patients Treated within Four Hours35 - Use of drains versus no drains after burr-hole evacuation of chronic subdural haematoma: a randomised controlled trial36 - Significance of intracranial hypertension in severe head injury37 - A randomized, double-blind study of phenytoin for the prevention of post-traumatic seizures38 - Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months.39 - Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension (RESCUEicp trial).40 - Surgical Management of Acute Epidural HematomasSection Six - Spine Trauma 41 - Validity of a Set of Clinical Criteria to Rule Out Injury to the Cervical Spine in Patients with Blunt Trauma42 - The subaxial cervical spine injury classification system: a novel approach to recognize the importance of morphology, neurology, and integrity of the disco-ligamentous complex43 - A new classification of thoracolumbar injuries: the importance of injury morphology, the integrity of the posterior ligamentous complex, and neurologic status44 - A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Use of Methylprednisolone Sodium SuccinateSection Seven - Spine 45 - Effect of High-dose Dexamethasone in Carcinomatous Metastatic Spinal Cord Compression Treated with Radiotherapy: a Randomised Trial46 - Direct Decompressive Surgical Resection in the Treatment of Spinal Cord Compression Caused by Metastatic Cancer: A Randomised Trial47 - Surgical vs nonoperative treatment for lumbar disc herniation: the Spine Patient Outcomes Research Trial (SPORT): a randomized trial48 - Cauda Equina Syndrome Secondary to Lumbar Disc Herniation: A Meta-Analysis of Surgical Outcomes49 - Surgical vs nonsurgical therapy for lumbar spinal stenosis50 - The anterior approach for removal of ruptured cervical disks