This book includes the outcomes of the 4th International Conference on Artificial Intelligence and Smart Data Science AISDS 2025.From big data analytics uncovering hidden patterns to predictive modeling shaping climate, health, and industry forecasts, AI is transforming every sector. Advances in sentiment analysis, healthcare diagnostics, workflow optimization, and smart recommender systems are redefining how we learn, heal, and connect. The future is intelligent—are you ready to lead it?