George Spratto is a former Dean and Professor of Pharmacology in the School of Pharmacy at West Virginia University. He uses his pharmacology expertise required to effectively edit monographs, research market changes, and prioritize drug inclusion for The 2013 EDITION DELMAR NURSE'S DRUG HANDBOOK™. Adrienne L. Woods worked in nursing for more than 35 years with the last 15 as a Nurse Practitioner. Her experience includes psychiatry; acute medical and surgical floors; medical, surgical, and coronary I.C.U.; and E.R. settings. She has also been nurse manager of an I.C.U. and a nursing supervisor of the Veteran's Administration Hospital in Wilmington, Delaware. Currently a clinical instructor and adjunct faculty member in the College of Nursing at the University of Delaware, she also works as a private consultant and with a professional union. Ms. Woods serves on a post-deployment team caring for Iraqi war veterans and polytrauma patients. In addition to various certifications, she was Awarded Delaware Nurse Practitioner Advocate by A.A.N.P. in 2009. Ms. Woods is a member of A.N.A., Sigma Theta Tau, A.A.N.P., and D.C.N.P.

• PREFACE ACKNOWLEDGMENTS QUICK REFERENCE GUIDE TO A DRUG MONOGRAPH CHAPTER A-Z Listing of Drugs CHAPTER Therapeutic Drug Classifications Alkylating Agents Alpha-1-Adrenergic Blocking Agents Aminoglycosides Amphetamines and Derivatives Angiotensin II Receptor Antagonists Angiotensin-Converting Enzyme (ACE) Inhibitors Antianginal Drugs—Nitrates/Nitrites Antiarrhythmic Drugs Anticonvulsants Antidepressants, Tricyclic Antidiabetic Agents: Hypoglycemic Agents Antidiabetic Agents: Insulins Antiemetics Antihistamines (H1 Blockers) Antihyperlipidemic Agents—HMG-CoA Reductase Inhibitors Antihypertensive AgentsAnti-Infective Drugs Antineoplastic Agents Antiparkinson Agents Antipsychotic Agents, Phenothiazines Antiviral Drugs Beta-Adrenergic Blocking Agents Calcium Channel Blocking Agents Calcium Salts Cephalosporins Cholinergic Blocking Agents vi Table of ContentsCorticosteroids Diuretics, Loop Diuretics, Thiazides Estrogens Fluoroquinolones Heparins, Low Molecular Weight Herbs Histamine H2 Antagonists Laxatives Narcotic Analgesics Narcotic Antagonists Neuromuscular Blocking Agents Nonsteroidal Anti-Inflammatory Drugs Oral Contraceptives: Estrogen-Progesterone Combinations Penicillins Progesterone and Progestins Proton Pump Inhibitors Selective Serotonin Reuptake Inhibitors Serotonin 5-HT1 Receptor Agonists (Antimigraine Drugs) Skeletal Muscle Relaxants, Centrally Acting Sulfonamides Sympathomimetic Drugs Tetracyclines Thyroid Drugs Tranquilizers/Antimanic Drugs/Hypnotics Vaccines Vitamins APPENDIX 1: Commonly Used Abbreviations and Symbols APPENDIX 2: Medication Errors: The Importance of Reporting APPENDIX 3: Controlled Substances in the United States and Canada APPENDIX 4: Pregnancy Categories: FDA Assigned APPENDIX 5: Calculating Body Surface Area and Body Mass Index APPENDIX 6: Elements of a Prescription APPENDIX 7: Easy Formulas for IV Rate Calculation APPENDIX 8: List of Combination Drugs APPENDIX 9: Drug/Food Interactions APPENDIX 10: Drugs Whose Effects are Modified by Grapefruit Juice APPENDIX 11: Drugs That Should Not Be Crushed APPENDIX 12: National Patient Safety Goals (NPSG)APPENDIX 13: Cultural Aspects of Medicine Therapy APPENDIX 14: Common Spanish Phrases and Terms Used in a Health Care SettingAPPENDIX 15: Medication Reconciliation/Overdose/Misuse IV INDEX INDEX

PREFACE ACKNOWLEDGMENTS QUICK REFERENCE GUIDE TO A DRUG MONOGRAPH CHAPTER A-Z Listing of Drugs CHAPTER Therapeutic Drug Classifications Alkylating Agents Alpha-1-Adrenergic Blocking Agents Aminoglycosides Amphetamines and Derivatives Angiotensin II Receptor Antagonists Angiotensin-Converting Enzyme (ACE) Inhibitors Antianginal Drugs-Nitrates/Nitrites Antiarrhythmic Drugs Anticonvulsants Antidepressants, Tricyclic Antidiabetic Agents: Hypoglycemic Agents Antidiabetic Agents: Insulins Antiemetics Antihistamines (H1 Blockers) Antihyperlipidemic Agents-HMG-CoA Reductase Inhibitors Antihypertensive Agents Anti-Infective Drugs Antineoplastic Agents Antiparkinson Agents Antipsychotic Agents, Phenothiazines Antiviral Drugs Beta-Adrenergic Blocking Agents Calcium Channel Blocking Agents Calcium Salts Cephalosporins Cholinergic Blocking Agents vi Table of Contents Corticosteroids Diuretics, Loop Diuretics, Thiazides Estrogens Fluoroquinolones Heparins, Low Molecular Weight Herbs Histamine H2 Antagonists Laxatives Narcotic Analgesics Narcotic Antagonists Neuromuscular Blocking Agents Nonsteroidal Anti-Inflammatory Drugs Oral Contraceptives: Estrogen-Progesterone Combinations Penicillins Progesterone and Progestins Proton Pump Inhibitors Selective Serotonin Reuptake Inhibitors Serotonin 5-HT1 Receptor Agonists (Antimigraine Drugs) Skeletal Muscle Relaxants, Centrally Acting Sulfonamides Sympathomimetic Drugs Tetracyclines Thyroid Drugs Tranquilizers/Antimanic Drugs/Hypnotics Vaccines Vitamins APPENDIX 1: Commonly Used Abbreviations and Symbols APPENDIX 2: Medication Errors: The Importance of Reporting APPENDIX 3: Controlled Substances in the United States and Canada APPENDIX 4: Pregnancy Categories: FDA Assigned APPENDIX 5: Calculating Body Surface Area and Body Mass Index APPENDIX 6: Elements of a Prescription APPENDIX 7: Easy Formulas for IV Rate Calculation APPENDIX 8: List of Combination Drugs APPENDIX 9: Drug/Food Interactions APPENDIX 10: Drugs Whose Effects are Modified by Grapefruit Juice APPENDIX 11: Drugs That Should Not Be Crushed APPENDIX 12: National Patient Safety Goals (NPSG) APPENDIX 13: Cultural Aspects of Medicine Therapy APPENDIX 14: Common Spanish Phrases and Terms Used in a Health Care Setting APPENDIX 15: Medication Reconciliation/Overdose/Misuse IV INDEX INDEX

George Spratto is a former Dean and Professor of Pharmacology in the School of Pharmacy at West Virginia University. He uses his pharmacology expertise required to effectively edit monographs, research market changes, and prioritize drug inclusion for The 2013 EDITION DELMAR NURSE'S DRUG HANDBOOK™. Adrienne L. Woods worked in nursing for more than 35 years with the last 15 as a Nurse Practitioner. Her experience includes psychiatry; acute medical and surgical floors; medical, surgical, and coronary I.C.U.; and E.R. settings. She has also been nurse manager of an I.C.U. and a nursing supervisor of the Veteran's Administration Hospital in Wilmington, Delaware. Currently a clinical instructor and adjunct faculty member in the College of Nursing at the University of Delaware, she also works as a private consultant and with a professional union. Ms. Woods serves on a post-deployment team caring for Iraqi war veterans and polytrauma patients. In addition to various certifications, she was Awarded Delaware Nurse Practitioner Advocate by A.A.N.P. in 2009. Ms. Woods is a member of A.N.A., Sigma Theta Tau, A.A.N.P., and D.C.N.P.

• PREFACE ACKNOWLEDGMENTS QUICK REFERENCE GUIDE TO A DRUG MONOGRAPH CHAPTER A-Z Listing of Drugs CHAPTER Therapeutic Drug Classifications Alkylating Agents Alpha-1-Adrenergic Blocking Agents Aminoglycosides Amphetamines and Derivatives Angiotensin II Receptor Antagonists Angiotensin-Converting Enzyme (ACE) Inhibitors Antianginal Drugs—Nitrates/Nitrites Antiarrhythmic Drugs Anticonvulsants Antidepressants, Tricyclic Antidiabetic Agents: Hypoglycemic Agents Antidiabetic Agents: Insulins Antiemetics Antihistamines (H1 Blockers) Antihyperlipidemic Agents—HMG-CoA Reductase Inhibitors Antihypertensive AgentsAnti-Infective Drugs Antineoplastic Agents Antiparkinson Agents Antipsychotic Agents, Phenothiazines Antiviral Drugs Beta-Adrenergic Blocking Agents Calcium Channel Blocking Agents Calcium Salts Cephalosporins Cholinergic Blocking Agents vi Table of ContentsCorticosteroids Diuretics, Loop Diuretics, Thiazides Estrogens Fluoroquinolones Heparins, Low Molecular Weight Herbs Histamine H2 Antagonists Laxatives Narcotic Analgesics Narcotic Antagonists Neuromuscular Blocking Agents Nonsteroidal Anti-Inflammatory Drugs Oral Contraceptives: Estrogen-Progesterone Combinations Penicillins Progesterone and Progestins Proton Pump Inhibitors Selective Serotonin Reuptake Inhibitors Serotonin 5-HT1 Receptor Agonists (Antimigraine Drugs) Skeletal Muscle Relaxants, Centrally Acting Sulfonamides Sympathomimetic Drugs Tetracyclines Thyroid Drugs Tranquilizers/Antimanic Drugs/Hypnotics Vaccines Vitamins APPENDIX 1: Commonly Used Abbreviations and Symbols APPENDIX 2: Medication Errors: The Importance of Reporting APPENDIX 3: Controlled Substances in the United States and Canada APPENDIX 4: Pregnancy Categories: FDA Assigned APPENDIX 5: Calculating Body Surface Area and Body Mass Index APPENDIX 6: Elements of a Prescription APPENDIX 7: Easy Formulas for IV Rate Calculation APPENDIX 8: List of Combination Drugs APPENDIX 9: Drug/Food Interactions APPENDIX 10: Drugs Whose Effects are Modified by Grapefruit Juice APPENDIX 11: Drugs That Should Not Be Crushed APPENDIX 12: National Patient Safety Goals (NPSG)APPENDIX 13: Cultural Aspects of Medicine Therapy APPENDIX 14: Common Spanish Phrases and Terms Used in a Health Care SettingAPPENDIX 15: Medication Reconciliation/Overdose/Misuse IV INDEX INDEX

PREFACE ACKNOWLEDGMENTS QUICK REFERENCE GUIDE TO A DRUG MONOGRAPH CHAPTER A-Z Listing of Drugs CHAPTER Therapeutic Drug Classifications Alkylating Agents Alpha-1-Adrenergic Blocking Agents Aminoglycosides Amphetamines and Derivatives Angiotensin II Receptor Antagonists Angiotensin-Converting Enzyme (ACE) Inhibitors Antianginal Drugs-Nitrates/Nitrites Antiarrhythmic Drugs Anticonvulsants Antidepressants, Tricyclic Antidiabetic Agents: Hypoglycemic Agents Antidiabetic Agents: Insulins Antiemetics Antihistamines (H1 Blockers) Antihyperlipidemic Agents-HMG-CoA Reductase Inhibitors Antihypertensive Agents Anti-Infective Drugs Antineoplastic Agents Antiparkinson Agents Antipsychotic Agents, Phenothiazines Antiviral Drugs Beta-Adrenergic Blocking Agents Calcium Channel Blocking Agents Calcium Salts Cephalosporins Cholinergic Blocking Agents vi Table of Contents Corticosteroids Diuretics, Loop Diuretics, Thiazides Estrogens Fluoroquinolones Heparins, Low Molecular Weight Herbs Histamine H2 Antagonists Laxatives Narcotic Analgesics Narcotic Antagonists Neuromuscular Blocking Agents Nonsteroidal Anti-Inflammatory Drugs Oral Contraceptives: Estrogen-Progesterone Combinations Penicillins Progesterone and Progestins Proton Pump Inhibitors Selective Serotonin Reuptake Inhibitors Serotonin 5-HT1 Receptor Agonists (Antimigraine Drugs) Skeletal Muscle Relaxants, Centrally Acting Sulfonamides Sympathomimetic Drugs Tetracyclines Thyroid Drugs Tranquilizers/Antimanic Drugs/Hypnotics Vaccines Vitamins APPENDIX 1: Commonly Used Abbreviations and Symbols APPENDIX 2: Medication Errors: The Importance of Reporting APPENDIX 3: Controlled Substances in the United States and Canada APPENDIX 4: Pregnancy Categories: FDA Assigned APPENDIX 5: Calculating Body Surface Area and Body Mass Index APPENDIX 6: Elements of a Prescription APPENDIX 7: Easy Formulas for IV Rate Calculation APPENDIX 8: List of Combination Drugs APPENDIX 9: Drug/Food Interactions APPENDIX 10: Drugs Whose Effects are Modified by Grapefruit Juice APPENDIX 11: Drugs That Should Not Be Crushed APPENDIX 12: National Patient Safety Goals (NPSG) APPENDIX 13: Cultural Aspects of Medicine Therapy APPENDIX 14: Common Spanish Phrases and Terms Used in a Health Care Setting APPENDIX 15: Medication Reconciliation/Overdose/Misuse IV INDEX INDEX

George Spratto is a former Dean and Professor of Pharmacology in the School of Pharmacy at West Virginia University. He uses his pharmacology expertise required to effectively edit monographs, research market changes, and prioritize drug inclusion for The 2013 EDITION DELMAR NURSE'S DRUG HANDBOOK™. Adrienne L. Woods worked in nursing for more than 35 years with the last 15 as a Nurse Practitioner. Her experience includes psychiatry; acute medical and surgical floors; medical, surgical, and coronary I.C.U.; and E.R. settings. She has also been nurse manager of an I.C.U. and a nursing supervisor of the Veteran's Administration Hospital in Wilmington, Delaware. Currently a clinical instructor and adjunct faculty member in the College of Nursing at the University of Delaware, she also works as a private consultant and with a professional union. Ms. Woods serves on a post-deployment team caring for Iraqi war veterans and polytrauma patients. In addition to various certifications, she was Awarded Delaware Nurse Practitioner Advocate by A.A.N.P. in 2009. Ms. Woods is a member of A.N.A., Sigma Theta Tau, A.A.N.P., and D.C.N.P.

• PREFACE ACKNOWLEDGMENTS QUICK REFERENCE GUIDE TO A DRUG MONOGRAPH CHAPTER A-Z Listing of Drugs CHAPTER Therapeutic Drug Classifications Alkylating Agents Alpha-1-Adrenergic Blocking Agents Aminoglycosides Amphetamines and Derivatives Angiotensin II Receptor Antagonists Angiotensin-Converting Enzyme (ACE) Inhibitors Antianginal Drugs—Nitrates/Nitrites Antiarrhythmic Drugs Anticonvulsants Antidepressants, Tricyclic Antidiabetic Agents: Hypoglycemic Agents Antidiabetic Agents: Insulins Antiemetics Antihistamines (H1 Blockers) Antihyperlipidemic Agents—HMG-CoA Reductase Inhibitors Antihypertensive AgentsAnti-Infective Drugs Antineoplastic Agents Antiparkinson Agents Antipsychotic Agents, Phenothiazines Antiviral Drugs Beta-Adrenergic Blocking Agents Calcium Channel Blocking Agents Calcium Salts Cephalosporins Cholinergic Blocking Agents vi Table of ContentsCorticosteroids Diuretics, Loop Diuretics, Thiazides Estrogens Fluoroquinolones Heparins, Low Molecular Weight Herbs Histamine H2 Antagonists Laxatives Narcotic Analgesics Narcotic Antagonists Neuromuscular Blocking Agents Nonsteroidal Anti-Inflammatory Drugs Oral Contraceptives: Estrogen-Progesterone Combinations Penicillins Progesterone and Progestins Proton Pump Inhibitors Selective Serotonin Reuptake Inhibitors Serotonin 5-HT1 Receptor Agonists (Antimigraine Drugs) Skeletal Muscle Relaxants, Centrally Acting Sulfonamides Sympathomimetic Drugs Tetracyclines Thyroid Drugs Tranquilizers/Antimanic Drugs/Hypnotics Vaccines Vitamins APPENDIX 1: Commonly Used Abbreviations and Symbols APPENDIX 2: Medication Errors: The Importance of Reporting APPENDIX 3: Controlled Substances in the United States and Canada APPENDIX 4: Pregnancy Categories: FDA Assigned APPENDIX 5: Calculating Body Surface Area and Body Mass Index APPENDIX 6: Elements of a Prescription APPENDIX 7: Easy Formulas for IV Rate Calculation APPENDIX 8: List of Combination Drugs APPENDIX 9: Drug/Food Interactions APPENDIX 10: Drugs Whose Effects are Modified by Grapefruit Juice APPENDIX 11: Drugs That Should Not Be Crushed APPENDIX 12: National Patient Safety Goals (NPSG)APPENDIX 13: Cultural Aspects of Medicine Therapy APPENDIX 14: Common Spanish Phrases and Terms Used in a Health Care SettingAPPENDIX 15: Medication Reconciliation/Overdose/Misuse IV INDEX INDEX

PREFACE ACKNOWLEDGMENTS QUICK REFERENCE GUIDE TO A DRUG MONOGRAPH CHAPTER A-Z Listing of Drugs CHAPTER Therapeutic Drug Classifications Alkylating Agents Alpha-1-Adrenergic Blocking Agents Aminoglycosides Amphetamines and Derivatives Angiotensin II Receptor Antagonists Angiotensin-Converting Enzyme (ACE) Inhibitors Antianginal Drugs-Nitrates/Nitrites Antiarrhythmic Drugs Anticonvulsants Antidepressants, Tricyclic Antidiabetic Agents: Hypoglycemic Agents Antidiabetic Agents: Insulins Antiemetics Antihistamines (H1 Blockers) Antihyperlipidemic Agents-HMG-CoA Reductase Inhibitors Antihypertensive Agents Anti-Infective Drugs Antineoplastic Agents Antiparkinson Agents Antipsychotic Agents, Phenothiazines Antiviral Drugs Beta-Adrenergic Blocking Agents Calcium Channel Blocking Agents Calcium Salts Cephalosporins Cholinergic Blocking Agents vi Table of Contents Corticosteroids Diuretics, Loop Diuretics, Thiazides Estrogens Fluoroquinolones Heparins, Low Molecular Weight Herbs Histamine H2 Antagonists Laxatives Narcotic Analgesics Narcotic Antagonists Neuromuscular Blocking Agents Nonsteroidal Anti-Inflammatory Drugs Oral Contraceptives: Estrogen-Progesterone Combinations Penicillins Progesterone and Progestins Proton Pump Inhibitors Selective Serotonin Reuptake Inhibitors Serotonin 5-HT1 Receptor Agonists (Antimigraine Drugs) Skeletal Muscle Relaxants, Centrally Acting Sulfonamides Sympathomimetic Drugs Tetracyclines Thyroid Drugs Tranquilizers/Antimanic Drugs/Hypnotics Vaccines Vitamins APPENDIX 1: Commonly Used Abbreviations and Symbols APPENDIX 2: Medication Errors: The Importance of Reporting APPENDIX 3: Controlled Substances in the United States and Canada APPENDIX 4: Pregnancy Categories: FDA Assigned APPENDIX 5: Calculating Body Surface Area and Body Mass Index APPENDIX 6: Elements of a Prescription APPENDIX 7: Easy Formulas for IV Rate Calculation APPENDIX 8: List of Combination Drugs APPENDIX 9: Drug/Food Interactions APPENDIX 10: Drugs Whose Effects are Modified by Grapefruit Juice APPENDIX 11: Drugs That Should Not Be Crushed APPENDIX 12: National Patient Safety Goals (NPSG) APPENDIX 13: Cultural Aspects of Medicine Therapy APPENDIX 14: Common Spanish Phrases and Terms Used in a Health Care Setting APPENDIX 15: Medication Reconciliation/Overdose/Misuse IV INDEX INDEX