Bio-Nanotechnology

Debasis Bagchi, PhD, MAC N, CNS, MAIC hE, University of Houston College of Pharmacy, Houston, Texas, USAManashi Bagchi, PhD, FAC N, NutriToday LLC, Boston, Massachusetts, USA Hiroyoshi Moriyama, PhD, FAC N, Showa Pharmaceutical University, Tokyo, JapanFereidoon Shahidi, PhD, FAC S, FAOC S, FCIC , FCI FST, FIA FoST, FIFT, FRSC, Department of Biochemistry, Memorial University of Newfoundland, St. John’s, Newfoundland, Canada

• Foreword xiPreface xiiContributors xvPART 1 INTRODUCTION 1Chapter 1 Biomedical Applications of Nanomaterials: An Overview 3Sunil K. Singh, Paresh P. Kulkarni, Debabrata DashChapter 2 The Challenge of Nanotechnology-Derived Food: Addressing the Concerns of the Public 33Tomiko YamaguchiChapter 3 Nanotechnology and Public Health: Contributions, Promises, and Premises 47Masami Matsuda, Ayako Goto, Toshio Ogino, Yoshiaki TanakaPART 2 NANOTECHNOLOGY IN NUTRITION AND MEDICINE 67Chapter 4 Functional Nanomaterials for Biomedical Research: Focus on Bio-Functionalization, Biosynthesis, and Biomedical Applications 69Murugan Veerapandian, Sathya Sadhasivam, Ramesh Subbiah, Kyusik YunChapter 5 An Overview of Nanoparticle-Assisted Polymerase Chain Reaction Technology 97Cenchao Shen, Zhizhou ZhangChapter 6 A Revolution in Nanomedicines 107Iulian Bobe, Mitsunori Harada, Ichiro NakatomiChapter 7 Nanotechnology for Regenerative Medicine 124Yoshikazu Kumashiro, Masayuki Yamato, Teruo OkanoPART 3 NANOTECHNOLOGY, HUMAN HEALTH AND APPLICATIONS 141Chapter 8 Novel Technologies for the Production of Functional Foods 143Jack Appiah Ofori, Yun-Hwa Peggy HsiehChapter 9 Nanomedicine: The Revolution of the Big Future with Tiny Medicine 163Danny D. MeetooChapter 10 Application of γ-Cyclodextrin in Nanomedicinal Foods and Cosmetics 179Yukiko Uekaji, Ayako Jo, Akihito Urano, Keiji TeraoChapter 11 Polymer-Based Nanocomposites for Food Packaging Applications 212Maurizio Avella, Roberto Avolio, Emilia Di Pace, Maria Emanuela Errico, Gennaro Gentile, Maria Grazia VolpeChapter 12 Ultrasound-Mediated Delivery Systems: Using Nano/Microbubbles or Bubble Liposomes 227Kazuo Maruyama, Ryo Suzuki, Yusuke Oda, Yoko Endo-Takahashi, Yoichi NegishiChapter 13 Nanoprobes and Quantum Dots: Employing Nanotechnology to Watch Biology 246Shampa ChatterjeeChapter 14 Enhanced Optical Biosensors Based on Nanoplasmonics 252Kyujung Kim, Youngjin Oh, Donghyun KimChapter 15 Nano-Biosensors for Mimicking Gustatory and Olfactory Senses 270Kiyoshi Toko, Takeshi Onodera, Yusuke TaharaChapter 16 Nanoparticles Inducing Simultaneous Bioreaction in Living Organisms: Critical Sizes for Transition of Biointeractive Behavior 292Fumio WatariChapter 17 Analysis of Immunological Reactions to Nanoscale Foods: Possible Occurrence of Allergic Reaction to Nanoscale Food Particles 304Eisuke F. Sato, Maki Hashimoto, Masayasu InoueChapter 18 An Overview of Green Nanotechnology 311Kelvii Wei GuoChapter 19 Characterization of Biopolymer and Chitosan-Based Nanocomposites with Antimicrobial Activity 355Jong-Whan RhimChapter 20 Nanotechnology and its Use in Agriculture 383Alejandro Pérez-de-Luque, M. Carmen HermosínChapter 21 Applications of Polymeric Nanoparticles with Steroids: A Review 399Megumu HigakiChapter 22 Nanocomposites for Food Packaging: An Overview 406Tie LanChapter 23 Nanotechnology in Cosmetic Products 414Howard A. Epstein, Alexander KielbassaChapter 24 Potential Medical Applications of Fullerenes: An Overview 424Seema Thakral, Naveen Kumar ThakralPART 4 NANOTECHNOLOGY AND OTHER VERSATILE DIVERSE APPLICATIONS 443Chapter 25 Biomedical Applications of Carbon-Based Nanomaterials 445Sunil K. Singh, Paresh P. Kulkarni, Debabrata DashChapter 26 Carbon Nanotubes and Their Application to Nanotechnology 464Wojtek Tutak, Sara Reynaud, Rajen B. PatelChapter 27 Characterization of Cyclodextrin Nanoparticles as Emulsifi ers 476Hiroyoshi Moriyama, Yoshihiro Saito, Debasis BagchiChapter 28 Application of Poly(γ -Glutamic Acid)-Based Nanoparticles as Antigen Delivery Carriers in Cancer Immunotherapy 487Kazuhiko Matsuo, Naoki Okada, Shinsaku NakagawaChapter 29 Basic Characterization of Nanobubbles and Their Potential Applications 506Seiichi Oshita, Tsutomu UchidaPART 5 NANOMATERIAL MANUFACTURING 517Chapter 30 Formulation and Characterization of Nanodispersions Composed of Dietary Materials for the Delivery of Bioactive Substances 519Takashi Kuroiwa, Jun Watanabe, Sosaku IchikawaChapter 31 Production of Nanoscale Foods Using High-Pressure Emulsifi cation Technology 531Kazuyuki TakagiChapter 32 Production of Monodisperse Fine Dispersions by Microchannel/Nanochannel Emulsification 542Isao Kobayashi, Marcos A. Neves, Sosaku Ichikawa, Takashi KuroiwaPART 6 APPLICATIONS OF MICROSCOPY AND NUCLEAR MAGNETIC RESONANCE IN NANOTECHNOLOGY 557Chapter 33 Applications of Atomic Force Microscopy in Food Nanotechnology 559Hiroshi Muramatsu, Junichi Wakayama, Kazumi Tsukamoto, Shigeru SugiyamaChapter 34 Applications of NMR to Biomolecular Systems of Interactions: An Overview 573Shinya Hanashima, Yoshiki YamaguchiPART 7 APPLICATIONS IN ENHANCING BIOAVAILABILITY AND CONTROLLING PATHOGENS 593Chapter 35 Bioavailability and Delivery of Nutraceuticals and Functional Foods Using Nanotechnology 595Hailong Yu, Qingrong HuangChapter 36 Encapsulation of Bioactive Compounds in Micron/Submicron-Sized Dispersions Using Microchannel Emulsifi cation or High-Pressure Homogenization 605Marcos A. Neves, Isao Kobayashi, Henelyta S. Ribeiro, Katerina B. FujiuChapter 37 Nanometric-Size Delivery Systems for Bioactive Compounds for the Nutraceutical and Food Industries 619Francesco Donsì, Mariarenata Sessa, Giovanna FerrariChapter 38 Nanoemulsion Technology for Delivery of Nutraceuticals and Functional-Food Ingredients 667Luz Sanguansri, Christine M. Oliver, Fernando Leal-CalderonChapter 39 Nanotechnology and Nonpolar Active Compounds in Functional Foods: An Application Note 697Philip J. BromleyPART 8 SAFETY, TOXICOLOGY AND REGULATORY ASPECTS 705Chapter 40 How Standards Inform the Regulation of Bio-nanotechnology 707Martha E. MarrapeseChapter 41 FDA and Nanotech: Baby Steps Lead to Regulatory Uncertainty 720Raj Bawa Chapter 42 Toxicity and Environmental Risks of Nanomaterials: An Update 733Paresh C. Ray, Anant Kumar Singh, Dulal Senapati, Zhen Fan, Hongtao Yu Chapter 43 Nanoparticle–Lung Interactions and Their Potential Consequences for Human Health 749Craig A. Poland, Martin J. D. CliftPART 9 FUTURE DIRECTIONS IN BIO-NANOTECHNOLOGY 777Chapter 44 Bio-Nanotechnology: A Journey Back to the Future 779Debasis Bagchi, Manashi Bagchi, Hiroyoshi Moriyama, Fereidoon ShahidiIndex 783Colour plate section 1 falls between pages 254 and 255Colour plate section 2 falls between pages 574 and 575