?Theoretical and Clinical Geropharmacology?

Dr. Atayik is currently working in the Department of General Surgery at Hacettepe University Faculty of Medicine. He has been working as a scientist and researcher with Prof. Ufuk Çakatay since 2017. His research interests are in the fields of aging, age-related disorders, redox biology, oncogenetics, melatonin, mitochondria, surgical advances, and developing novel techniques for modern surgery. Dr. Atayik has conducted clinical research and experimental studies. He has published many scientific papers, such as research papers, narrative reviews, and book chapters, and has worked as an author, referee, editorial assistant, and guest editor, and editor in many prominent publishing houses. He was awarded the Young Investigator Presentation Prize at the VIII. International Congress of Molecular Medicine, which was held in Istanbul, Turkey, in November 2021.Ufuk Çakatay (May 09, 1965 –) is a Turkish biochemist and biogerontologist. He is a full professor of medical biochemistry at Istanbul-University Cerrahpaşa in Istanbul, Turkey. He has a long-standing interest in oxidative protein damage, redox signaling, and biomarkers of proteostasis. Much less is known about the relationship between redox signaling events and senescent cells. However, it has been shown that the number of senescent cells in many tissues increases with age and that senescent cells are found in various age-related diseases. The development of experimental animal models for age-related disorders and the optimization of various bioanalytical techniques for the assessment of redox status in aging tissue are among his major research interests. Professor Çakatay has authored more than 100 publications in several leading journals, including research papers, book chapters, editorials, and invited reviews on free radical biology, aging, diabetes, redox signaling, and senotherapeutics. He has been a guest editor, reviewer, and editorial board member for more than 50 journals. In addition, Professor Çakatay has a keen interest in mentoring medical students and promoting their research careers. He has received several prestigious awards, including the Top Reviewer Award from Elsevier Science Publishing, and was a former member of the Animal Research and Ethics Committee of Istanbul University.

• 1. Senotherapeutics: Milestones, innovations, and future prospectsUfuk Çakatay, Erdem Atasever and Mehmet Can Atayik2. Game Changer: Navigating between challenges and hopes in GeropharmacologyQian Chen, Lindon Young, Reid Hartman, Lidia Dankiv, Emily Yan and Robert Barsotti3. Next-Gen Senotherapeutics: AI/ML-driven strategies for aging and age-related disordersKavitha Thirumurugan, Prashanth S. Javali, Subhajit Sarkar, Ashish Kumar, Sree Varshini R and Jose Mathew D4. Pharmacological frontiers in senescence: Transforming senescence with drug repurposing :Andleeb Shahzadi, Sibel Ozyazgan and Ufuk Çakatay5. Pharmacological potential of calorie restriction mimetics in mitigating brain agingAbhishek Kumar Singh6. Isothiocyanates from cruciferous plants as geroprotectorsVolodymyr I. Lushchak7. Cellular parabiosis as a senotherapeutic approachIlhan Onaran and Sevide Şencan8. Molecular imaging for senescent cells-targeted therapeutics in aging and age-related diseasesPeili Cen9. Mitochondria-associated membranes (MAMs) in age-related heart diseases, role of endoplasmic reticulum stressAlejandro Silva-Palacios10. Cellular senescence and senotherapeutics in cardiovascular diseasesArttatrana Pal11. Risk of senescence, polypharmacy, and their outcomes in elderly cardiovascular disease patientsTamer Cebe and Fatih Kızılyel12. Geropharmacology and gastrointestinal surgeryAnıl Orhan13. Oxygen-ozone adjunct therapy in aging and senescence-related disorders. State of artSalvatore Chirumbolo, Giovanni Ricevuti, Marianno Franzini and Francesco Vaiano14. Polypharmacy-induced changes in the oral mucosa and jawbone in elderlyMehmet Yaltırık, Kaan Erisildar and Sabahat Zeynep Yey Özkeskin15. Senotherapeutic approach to age-related endocrine diseasesGülnur Andican and Şeydanur Turgut16. Polypharmacy as a reason for misinterpreting laboratory results in the elderly.Ibrahim Murat Bolayırlı