The abortifacient RU-486 was born in the laboratory, but its history has been shaped by legislators, corporate marketing executives, and protesters on both sides of the abortion debate. This volume explores how society decides what to do when discoveries such as RU-486 raise complex and emotional policy issues. Six case studies with insightful commentary offer a revealing look at the interplay of scientists, interest groups, the U.S. Congress, federal agencies, and the public in determining biomedical public policy--and suggest how decision making might become more reasoned and productive in the future. The studies are fascinating and highly readable accounts of the personal interactions behind the headlines. They cover dideoxyinosine (ddI), RU-486, Medicare coverage for victims of chronic kidney failure, the human genome project, fetal tissue transplantation, and the 1975 Asilomar conference on recombinant DNA.
Kathi E. Hanna, Editor; Committee to Study Decision Making, Division of Health Sciences Policy
1 Front Matter; 2 Introduction; 3 Unproven AIDS Therapies: he Food and Drug Administration and ddI; 4 A Political History of RU-486; 5 The Human Genome Project: The Formation of Federal Policies in the United States, 1986-1990; 6 Origins of the Medicare Kidney Disease Entitlement: The Societal Security Amendments of 1972; 7 Deliberations of the Human Fetal Tissue Transplantation Research Panel; 8 Asilomar and Recombinant DNA: The End of the Beginning; 9 Conclusions; 10 Appendix A: The Public and the Expert in Biomedical Policy Controversies; 11 Appendix B: Biographical Notes on the Authors and Commentators; 12 Index
National Research Council, Division of Behavioral and Social Sciences and Education, Institute of Medicine, and Families Board on Children, Youth, Steve Olson
Institute of Medicine, Board on the Health of Select Populations, and Transgender Health Issues and Research Gaps and Opportunities Committee on Lesbian, Gay, Bisexual
Institute of Medicine, Board on Population Health and Public Health Practice, Division of Health Promotion and Disease Prevention, Division of International Health
Institute of Medicine, Committee to Develop Methods Useful to the Department of Veteran Affairs in Estimating Its Physician Requirements, Joseph Lipscomb
Institute of Medicine, Board on Health Sciences Policy, Medical Follow-Up Agency, Committee on Alternative Funding Strategies for DOD's Peer Reviewed Medical Research Programs, Kathi E. Hanna, Michael McGeary
Institute of Medicine, Board on Health Sciences Policy, and Medical Devices Roundtable on Research and Development of Drugs, Biologics, Andrew Pope, Peter Bouxsein, Frederick J. Manning, Kathi E. Hanna
Institute of Medicine, Committee on Assessing the System for Protecting Human Research Participants, Laura Lyman Rodriguez, Kathi E. Hanna, Daniel D. Federman
National Research Council, Policy and Global Affairs, and Law Committee on Science, Technology, Committee on Daubert Standards, Anne-Marie Mazza, Kathi E. Hanna
Institute of Medicine, Division of Health Sciences Policy, Committee on Addressing Career Paths for Clinical Research, Mark A. Randolph, William N. Kelley
Institute of Medicine, Division of Health Sciences Policy, and Medical Devices Roundtable on Research and Development of Drugs, Biologics, Jonathan R. Davis, Sarah Pitluck, Peter Bouxsein, Ronald W. Estabrook, M.D. Yaffe, Sumner
Institute of Medicine, Division of Biobehavioral Sciences and Mental Disorders, Division of Health Sciences Policy, Committee on a National Neural Circuitry Database, Joseph B. Martin, Constance M. Pechura