Xenotransplantation involves the transplantation of cells, tissues, and whole organs from one species to another. Interest in animal-to-human xenotransplants has been spurred by the continuing shortage of donated human organs and by advances in knowledge concerning the biology of organ and tissue rejection. The scientific advances and promise, however, raise complex questions that must be addressed. This book considers the scientific and medical feasibility of xenotransplantation and explores the ethical and public policy issues surrounding the possibility of renewed clinical trials. The volume focuses on the science base of xenotransplantation, public health risks of infectious disease transmission, and ethical and public policy issues, including the views of patients and their families.
Committee on Xenograft Transplantation: Ethical Issues and Public Policy, Institute of Medicine
1 Front Matter; 2 Executive Summary; 3 1. Setting the Stage; 4 2. Assessing the Science Base; 5 3. Infectious Disease Risk to Public Health Posed By Xenografting; 6 4. Ethics and Public Policy; 7 5. Conclusions and Recommendations; 8 References; 9 Appendix A-Workshop Agenda; 10 Appendix B-List of Participants; 11 Appendix C-Immunosuppression in Allotransplantation
National Research Council, Division of Behavioral and Social Sciences and Education, Institute of Medicine, and Families Board on Children, Youth, Steve Olson
Institute of Medicine, Board on the Health of Select Populations, and Transgender Health Issues and Research Gaps and Opportunities Committee on Lesbian, Gay, Bisexual
Institute of Medicine, Board on Population Health and Public Health Practice, Division of Health Promotion and Disease Prevention, Division of International Health
Institute of Medicine, Committee to Develop Methods Useful to the Department of Veteran Affairs in Estimating Its Physician Requirements, Joseph Lipscomb