Uptake and Trafficking of Protein Toxins

Häftad, Engelska, 2018

2 199 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt för medlemmar vid köp för minst 249 kr.

This volume focuses on the transport of medically relevant bacterial protein toxins into mammalian cells, and on novel pharmacological strategies to inhibit toxin uptake.

Produktinformation

Utgivningsdatum2018-08-30
Mått155 x 235 x 15 mm
Vikt406 g
FormatHäftad
SpråkEngelska
SerieCurrent Topics in Microbiology and Immunology
Antal sidor256
FörlagSpringer International Publishing AG
ISBN9783319865027

Tillhör följande kategorier

Two feet on the membrane: uptake of clostridial neurotoxins.- Receptors and binding structures for Clostridium difficile Toxins A and B.- Cell entry of C3 exoenzyme from Clostridium botulinum.- Receptor-binding and up-take of binary actin-ADP-ribosylating toxins.- Clostridial Binary Toxins: Basic Understandings that Include Cell-Surface Binding and an Internal “Coup de Grace”.- Host cell chaperones Hsp70/Hsp90 and peptidyl-prolyl cis/trans isomerases are required for the membrane translocation of bacterial ADP-ribosylating toxins.- Multivalent Inhibitors of Channel-Forming Bacterial Toxins.- Toxin Transport by A-B Type of Toxins in Eukaryotic Target Cells and its inhibition by Positively Charged Heterocyclic Molecules.