Tumor Dormancy, Quiescence, and Senescence, Volume 2

Aging, Cancer, and Noncancer Pathologies

Inbunden, Engelska, 2013

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In this second volume in the series exploring Tumor Dormancy, Quiescence, and Cellular Senescence, discussion is focused on the role of tumor dormancy in diseases such as breast cancer, melanoma, prostate cancer, liver cancer and lung cancer.

Produktinformation

Utgivningsdatum2013-12-16
Mått178 x 254 x 25 mm
Vikt852 g
FormatInbunden
SpråkEngelska
SerieTumor Dormancy and Cellular Quiescence and Senescence
Antal sidor320
Upplaga2014
FörlagSpringer
ISBN9789400777255

Tillhör följande kategorier

Onkologi inom Medicin
Medicinsk utrustning och medicinska tekniker inom Medicin
Biovetenskap inom Naturvetenskap och teknik

Preface. I Molecular Mechanisms.- Asymmetric Dimethylarginine Accelerates Cellular Senescence.- Membrane-Derived Extracellular Vesicles from Endothelial Progenitor Cells Activate Angiogenesis.- Induction of P21-Dependent Senescence: Role of NAE Inhibitor MLN4924.- Regulation of the Novel Senescence Pathway by SKP2 E3 Ligase.- Oncogene-Induced Senescence: Role of Mitochondrial Dysfunction.- Interleukin- 6 induces Premature Senescence Involving Signal Transducer and Activator of Transcription 3 and Insulin-Like Growth Factor-Binding Protein 5.- A Role for the Nuclear Lamina Shape in Cell Senescence and Aging.- Upregulation of Alpha-2-Macroglobulin in Replicative Senescence.- Elevation of Ceramide in Senescence: Role of Sphingolipid Metabolism.- Molecular Signals Underlying Hair Follicle Morphagenesis and Cutaneous Regeneration.- Role of Chromatin –Remodeling Factor Jun Dimerization Protein 2 (JDP2) in Cellular Senescence.- Induction of Cellular Senescence: Role of Mitogen-Activated Protein Kinase-Interacting Kinase 1.- Mechanisms of Premature Cell Senescence. II Tumor And Cancer.- Nuclear Protein Pirin Negates the Cellular Senescence Barrier Against Cancer Development.- Defects in Chromatin Structure and Diseases.- The Role of Fibrosis in Tumor Progression and the Dormant to Proliferative Switch.- Diagnosis of Branchial Cyst Carcinoma: Role of Stem Cells and Dormancy.- Function of ING Proteins in Cancer and Senescence.- Premalignancy and Cellular Senescence.- Loss of CDH1 Triggers Premature Senescence in Part Via Activation of Both the RB/E2F1 and the Claspin/CHK1/P53 Tumor Suppressor Pathways.- Suppression of Premature Senescence and Promotion of Metastatic Transformation: Role of Reduced TGF-Beta Signaling in Human Cancer Progression.- Senescence Escape in Melanoma: Role of Spleen Tyrosine Kinase SYK.- Micrometastatic Cancer Cells: Role of Tumor Dormancy in Non-Small Cell Lung Cancer. III Quiescent Cd4+ T Cells Inhibit Multiples Stages Of Hiv Infection StemCells And Cancer Stem Cells.- Senescent-Derived Pluripotent Stem Cells are able to Redifferentiate into Fully Rejuvenated Cells.- The Transcription Factor Gata2 Regulates Quiescence in Haematopoietic Stem and Progenitor Cells.- Dormancy and Recurrence of Cancer Stem Cells in Bone: Role of Bone Morphogenetic Proteins.- Role of Microenvironment in Regulating Stem Cell and Tumor Initiating Cancer Cell Behavior and its Potential Therapeutic Implications.- Index.