Nathan Rosenberg, Annetine C. Gelijns, and Holly Dawkins, Editors; Committee on Technological Innovation in Medicine, Institute of Medicine

• 1 FRONT MATTER; 2 PART I: SETTING THE STAGE; 3 1 THE CHANGING NATURE OF MEDICAL TECHNOLOGY DEVELOPMENT; 4 2 RECENT TRENDS IN SUPPORT FOR BIOMEDICAL RESEARCH AND DEVELOPMENT; 5 PART II: MEDICAL DEVICE INNOVATION; 6 3 PHYSICIANS AND PHYSICISTS: THE INTERDISCIPLINARY INTRODUCTION OF THE LASER TO MEDICINE; 7 4 FROM THE SCALPEL TO THE SCOPE: ENDOSCOPIC INNOVATIONS IN GASTROENTEROLOGY, GYNECOLOGY, AND SURGERY; 8 5 COCHLEAR IMPLANTATION: ESTABLISHING CLINICAL FEASIBILITY, 1957-1982; 9 6 INNOVATION IN CARDIAC IMAGING; 10 PART III: BIOTECHNOLOGY INNOVATION; 11 7 INCENTIVES AND FOCUS IN UNIVERSITY AND INDUSTRIAL RESEARCH: THE CASE OF SYNTHETIC INSULIN; 12 8 THE DIVISION OF INNOVATIVE LABOR IN BIOTECHNOLOGY; 13 PART IV: CONCLUDING OBSERVATIONS; 14 9 PERSPECTIVES ON INDUSTRIAL R&D MANAGEMENT; 15 10 THE INTERWINING OF PUBLIC AND PROPRIETARY IN MEDICAL TECHNOLOGY; 16 APPENDIXES; 17 APPENDIX A: WORKSHOP AGENDA; 18 APPENDIX B: CONTRIBUTORS; 19 INDEX

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Nathan Rosenberg, Annetine C. Gelijns, and Holly Dawkins, Editors; Committee on Technological Innovation in Medicine, Institute of Medicine

• 1 FRONT MATTER; 2 PART I: SETTING THE STAGE; 3 1 THE CHANGING NATURE OF MEDICAL TECHNOLOGY DEVELOPMENT; 4 2 RECENT TRENDS IN SUPPORT FOR BIOMEDICAL RESEARCH AND DEVELOPMENT; 5 PART II: MEDICAL DEVICE INNOVATION; 6 3 PHYSICIANS AND PHYSICISTS: THE INTERDISCIPLINARY INTRODUCTION OF THE LASER TO MEDICINE; 7 4 FROM THE SCALPEL TO THE SCOPE: ENDOSCOPIC INNOVATIONS IN GASTROENTEROLOGY, GYNECOLOGY, AND SURGERY; 8 5 COCHLEAR IMPLANTATION: ESTABLISHING CLINICAL FEASIBILITY, 1957-1982; 9 6 INNOVATION IN CARDIAC IMAGING; 10 PART III: BIOTECHNOLOGY INNOVATION; 11 7 INCENTIVES AND FOCUS IN UNIVERSITY AND INDUSTRIAL RESEARCH: THE CASE OF SYNTHETIC INSULIN; 12 8 THE DIVISION OF INNOVATIVE LABOR IN BIOTECHNOLOGY; 13 PART IV: CONCLUDING OBSERVATIONS; 14 9 PERSPECTIVES ON INDUSTRIAL R&D MANAGEMENT; 15 10 THE INTERWINING OF PUBLIC AND PROPRIETARY IN MEDICAL TECHNOLOGY; 16 APPENDIXES; 17 APPENDIX A: WORKSHOP AGENDA; 18 APPENDIX B: CONTRIBUTORS; 19 INDEX

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Nathan Rosenberg, Annetine C. Gelijns, and Holly Dawkins, Editors; Committee on Technological Innovation in Medicine, Institute of Medicine

• 1 FRONT MATTER; 2 PART I: SETTING THE STAGE; 3 1 THE CHANGING NATURE OF MEDICAL TECHNOLOGY DEVELOPMENT; 4 2 RECENT TRENDS IN SUPPORT FOR BIOMEDICAL RESEARCH AND DEVELOPMENT; 5 PART II: MEDICAL DEVICE INNOVATION; 6 3 PHYSICIANS AND PHYSICISTS: THE INTERDISCIPLINARY INTRODUCTION OF THE LASER TO MEDICINE; 7 4 FROM THE SCALPEL TO THE SCOPE: ENDOSCOPIC INNOVATIONS IN GASTROENTEROLOGY, GYNECOLOGY, AND SURGERY; 8 5 COCHLEAR IMPLANTATION: ESTABLISHING CLINICAL FEASIBILITY, 1957-1982; 9 6 INNOVATION IN CARDIAC IMAGING; 10 PART III: BIOTECHNOLOGY INNOVATION; 11 7 INCENTIVES AND FOCUS IN UNIVERSITY AND INDUSTRIAL RESEARCH: THE CASE OF SYNTHETIC INSULIN; 12 8 THE DIVISION OF INNOVATIVE LABOR IN BIOTECHNOLOGY; 13 PART IV: CONCLUDING OBSERVATIONS; 14 9 PERSPECTIVES ON INDUSTRIAL R&D MANAGEMENT; 15 10 THE INTERWINING OF PUBLIC AND PROPRIETARY IN MEDICAL TECHNOLOGY; 16 APPENDIXES; 17 APPENDIX A: WORKSHOP AGENDA; 18 APPENDIX B: CONTRIBUTORS; 19 INDEX

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