Serpin Family

Proteins with Multiple Functions in Health and Disease

Häftad, Engelska, 2016

AvMargarethe Geiger,Felix Wahlmüller,Margareta Furtmüller

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The book provides an comprehensive overview on biology, genetics and cellular functions of serpins (serine protease inhibitors) in health and disease.

Produktinformation

Utgivningsdatum2016-08-23
Mått155 x 235 x 19 mm
Vikt517 g
FormatHäftad
SpråkEngelska
Antal sidor329
FörlagSpringer International Publishing AG
ISBN9783319349008

Tillhör följande kategorier

Kemi inom Naturvetenskap och teknik
Medicinsk utrustning och medicinska tekniker inom Medicin
Biokemi inom Naturvetenskap och teknik
Cellbiologi inom Naturvetenskap och teknik

Univ. Prof. Dr. Margarethe Geiger Department of Vascular Biology and Thrombosis Research, Center of Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstrasse 17, 1090 Wien Margarethe Geiger is a professor of vascular physiology at the Medical University of Vienna. Her research is focused on the role of non-inhibitory serine protease inhibitors in cell signaling. Dr. Margareta Furtmüller Department of Vascular Biology and Thrombosis Research, Med. Univ. Vienna, Schwarzspanierstrasse 17, 1090 Wien, email: margareta.furtmueller@meduniwien.ac.at Dr. Felix Wahlmüller Department of Vascular Biology and Thrombosis Research, Med. Univ. Vienna, Schwarzspanierstrasse 17, 1090 Wien, email: felix.wahlmueller@meduniwien.ac.at

1. Serpin Evolution and Genetics.- 2. Serpin Structure and Mechanism.- 3. New Serpins / New Functions of Serpins in Coagulation, Fibrinolysis, and Angiogenesis.- 4. Serpins in Development and Reproduction.- 5. Intracellular clade B serpins, intracellular functions of other serpins.- 6. Interaction of Serpins with Membrane-anchored Proteases.- 7. Serpins in Neurobiology.- 8. Serpins in Inflammation and Infectious Diseases.- 9. Cellular Proteostasis Systems Responsible for Orchestrating SERPIN Conformational Maturation and/or Disposal.- 10. SERPIN-related Diseases: Cellular Injury, Disease Modifiers, and Therapeutic Approaches.- 11. Serpins in Cancer.- 12. Non-mammalian Serpins.- 13. Serpins and Signal Transduction.- 14. Non-inhibitory serpins: structures and functions.- 15. (Patho)-physiology and/or novel functions of human serpins (in particular: vaspin) Serpins in animal models.