Del i serien Micro and Nano Technologies

Pharmaceutical Applications of Dendrimers

Häftad, Engelska, 2019

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Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. The book discusses the diagnostic applications of dendrimers, including their use as MRI contrast agents and in the imaging of diseased areas. In addition, the anti-inflammatory, antimicrobial and antiviral properties of PPI and PAMAM are also covered, along with a discussion on photosensitizers, such as rose Bengal and protoporphyrin IX that have been delivered using PAMAM and PPI dendrimers for the treatment of cancer.

This book is an important research reference for those who want to learn more about the development of dendrimer-based solutions for drug delivery.

Explores the role of dendrimers in the design of dendritic nanoplatforms for targeted drug and gene delivery systems
Discusses the potential of dendrimers in preformulation and formulation development
Addresses both clinical and regulatory challenges in the development of dendrimer-based formulations

Produktinformation

Utgivningsdatum2019-11-15
Mått191 x 235 x undefined mm
Vikt750 g
FormatHäftad
SpråkEngelska
SerieMicro and Nano Technologies
Antal sidor398
FörlagElsevier Science
ISBN9780128145272

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Abhay Singh Chauhan is Associate Professor, School of Pharmacy at the Medical College of Wisconsin, USA. He was previously Director of Pharmaceutical Nanotechnology at Concordia University, USA. His research is in the area of nanopharmaceuticals. Dr. Hitesh Kulhari is an Assistant Professor at the School of Nano Sciences, Central University of Gujarat, India. He completed his PhD at RMIT University, Australia, from 2011 to 2015. Prior to that, he earned his Master of Pharmacy at the Bundelkhand University, India, in 2008.Dr. Kulhari's remarkable contributions have been recognized with prestigious awards, including the Prof CNR Rao Research Excellence Award in Material Science, the INSPIRE Faculty Award, and the Early Career Research Award. His research interests include nanomedicines and nanobiomaterials.

1. Dendrimers: Introduction, types and properties2. Dendrimers as solubility enhancer or excipient3. Dendrimers as therapeutic agent/drug4. Biocompatibility and toxicity of dendrimers5. Dendrimers as drug delivery carrier6. Dendrimers for the delivery of biological drugs7. Pharmacokinetic considerations in design of dendrimer-based nanomedicines8. Design of dendrimer-based prodrugs9. Stimuli-responsive dendrimers in drug delivery10. Dendrimer-based targeted drug delivery11. Dendrimers in photodynamic therapy12. Diagnostic applications of dendrimer based nanovectors13. Overview of current clinical status of dendrimer-based formulations