Metallothionein III

Inbunden, Engelska, 1993

699 kr

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Focuses on the biological roles and medical implications of metallothioneins, and related chemical and biochemical developments. The contributors present and discuss findings on the roles of metallothionein in various kinds of stress conditions, including exposure to heavy metals.

Produktinformation

Utgivningsdatum1993-01-01
Mått168 x 240 x 33 mm
Vikt1 000 g
FormatInbunden
SpråkEngelska
SerieAdvances in Life Sciences
Antal sidor483
Upplaga1993
FörlagBirkhauser Verlag AG
ISBN9783764327699

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Biokemi inom Naturvetenskap och teknik

Part 1 Introductory overview: the functional potential and potential functions of metallothioneins - a personal perspective, B.L. Valee and W. Maret. Part 2 Overview: evolution, structure and chemical activity of class I metallothioneins - an overview, J.H.R. Kagi; dynamic aspects of metallothionein structure, J. Otvos et al; quantification of metallothionein in biological materials, K.H. Summer and D. Klein. Part 3 Biological function: biological functions of metallothionein - a review, M.G. Cherian and H.M. Chan; involvement of metallothionein in the regulation of mineral metabolism, I. Bremner; induction of metallothionein synthesis by oxidative stress and possible role in acute phase response, M. Sato et al; response of invertebrate metallothioneins and MT genes to metals and implications for environmental toxicology, G. Roesijadi; indirect induction of metallothionein by organic compounds, K.S. Min et al; nuclear and cytoplasmic localization of metallothionein in human liver during development and in tumor cells, M.G. Cherian; 125I-metallothionein binding to spermatozoa, K. Nakajima et al; degradation of metallothionein, C.D. Klaassen et al; gamma-glutamylcysteinyl isopeptides - structure, synthesis and metal-binding complexes, W.E. Rauser. Part 4 Medical implications: medical implications of metallothionein, M.P. Waalkes; utilization of metallothionein inducer in cancer therapy, A. Naganuma et al; clinical use of a bismuth compound as an adjunct in chemotherapy with "cis"-DDP against human urogenital tumors, Y. Kondo et al; the role of metallothionein for the reduction of adverse effect of cisplatin and the induction of resistance to cisplatin, N. Saijo et al; regulation of metallothionein expression and cellular resistance to electrophilic antineoplastic agents, J.S. Lazo et al; the tumor suppressive activity of cadmium, M.P. Waalkes et al; growth inhibitory factor in brain, Y. Uchida; metallothionein in tumor and host - intersections of zinc metabolism, the stress response and tumor therapy, D.H. Petering et al. Part 5 Molecular and cellular biology: molecular genetics of metallothionein - an overview, D.H. Hamer; cell-specific expression and regulation of the mouse metallothionein-I and -II genes in the reproductive tract and preimplantation embryo, G.K. Andrews et al; regulation of human and rainbow trout metallothionein genes, L. Gedamu et al; the metallothionein structural motif involved in metalloregulation, D.R. Winge and C.T. Dameron; metallothionein genes and their regulation in transgenic mice, R.D. Palmiter et al; metallothionein structure/function interface, P.C Huang; the relation between nuclear localization of metallothionein and proliferation of rat hepatocytes, K. Tsujikawa et al; regulation of metallothionein biosynthesis in genital organs of male rats, C. Tohyama et al; factors involved in the transcriptional regulation of metallothionein genes, S. Koizumi and F. Ohtsuka.