Fundamentals of Molecular Virology

Nicholas H. Acheson, Ph.D., is Emeritus Professor of Microbiology and Immunology at McGill University, Montreal, Quebec, Canada.

• Section I: Introduction to Virology 1. Introduction to Virology 2Nicholas H. Acheson2. Virus Structure and Assembly 18Stephen C. Harrison3. Virus Classification: The World of Viruses 31Nicholas H. Acheson4. Virus Entry 45Ari HeleniusSection II: Viruses of Bacteria and Archaea5. Single-Stranded RNA Bacteriophages 59Jan van Duin6. Microviruses 69Bentley Fane7. Bacteriophage T7 77William C. Summers8. Bacteriophage Lambda 85Michael Feiss9. Viruses of Archaea 97David PrangishviliSection III: Positive-Strand RNA Viruses of Eukaryotes10. Cucumber Mosaic Virus 112Ping Xu, Marilyn J. Roosinck11. Picornaviruses 125Bert L. Semler12. Flaviviruses 137Richard Kuhn13. Togaviruses 148Milton Schlesinger, Sondra Schlesinger, Richard Kuhn14. Coronaviruses 159Mark Denison, Michelle M. BeckerSection IV: Negative-Strand and Double-Stranded RNA Viruses of Eukaryotes15. Paramyxoviruses and Rhabdoviruses 175Nicholas H. Acheson, Daniel Kolakofsky, Christopher Richardson, Laurent Roux16. Filovirouses 188Heinz Feldman, Hans-Dieter Klenk, Nicholas H. Acheson17. Bunyaviruses 200Richard M. Elliott18. Influenza Viruses 225Terence S. Dermody, James D. Chappell19. Reoviruses 225Terence S. Dermody, James D. ChappellSection V: Small DNA Viruses of Eukaryotes20. Parvoviruses 238Peter Beard21. Polyomaviruses 247Nicholas H. Acheson22. Papillomaviruses 263Greg Matlashewski, Lawrence BanksSection VI: Larger DNA Viruses of Eukaryotes23. Adenoviruses 274Philip Branton24. Herpesviruses 285Bernard Roisman, Gabriella Campadelli-Fiume, Richard Longnecker25. Baculoviruses 302Eric B. Carstens26. Poxviruses 312Richard C. Condit27. Viruses of Algae and Mimivirus 325Michael J. Allen, William H. WilsonSection VII: Viruses That Use A Reverse Transcriptase28. Retroviruses 342Alan Cochrane29. Human Immunodeficiency VirusAlan Cochrane30. Hepadnaviruses 365Christopher RichardsonSection VIII: Viroids and Prions31. Viroids and Hepatitis Delta Virus 378Jean-Pierre Perreault, Martin Pelchat32. Prions 387Dalius J. BriedisSection IX: Host Defenses Against Virus Infection33. Intrinsic Cellular Defenses Against Virus Infection 398Karen Mossman, Pierre Geninm, John Hiscott34. Innate and Adaptive Immune Responses to Virus Infection 415Malcolm G. Baines, Karen MossmanSection X: Antiviral Agents and Virus Vectors35. Antiviral Vaccines 428Brian Ward36. Antiviral ChemotherapyDonald M. Coen37. Eukaryotic Virus Vectors 456GLOSSARY 471CREDITS 484NAME INDEX 489SUBJECT INDEX 491Rénald Gilbert, Bernard Massie

“I like the overall organization and “directness” in the writing. The chapter outlines that cover the basic features of the virus discussed are quite useful. The illustrations are clear and easy to interpret.”  -Michael Graves, University of Massachusetts – Lowell “Having each chapter that covers a specific virus written by an expert in the field then having Acheson bring the material into a common style is an excellent approach. I enjoy the slight stylistic differences that I find in the chapters, but Acheson has a direct and concise approach that makes the information throughout the text understandable for students. Chapters are short and direct. The table of contents is informative. Sections within the chapters are logically organized and headings are informative. The boxes provide interesting side topics in an extremely concise manner. Overall, I find Acheson to be an excellent text.” -William Tapprich, University of Nebraska – Omaha“The conceptual approach to virus biology is the greatest strength of the text. The book has the appropriate level of molecular detail and it is presented in a manner that an undergraduate can readily grasp. It is a highly readable text.” -Sharon Roberts, Auburn University