Form and Function of Mammalian Lung: Analysis by Scientific Computing

Häftad, Engelska, 1998

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This volume addresses topics including: analysis of form and function of the mammalian lung by scientific computing; generation of a computer lung model; morphological analysis and representation of the branching pattern of mammalian lung; functional simulation of gas transport; 3-D visualization of an acinus; colour-coded visualization of gas transport; new insights into form and function of the lung; new morphological techniques.

Produktinformation

Utgivningsdatum1998-10-15
Mått155 x 235 x undefined mm
Vikt195 g
FormatHäftad
SpråkEngelska
SerieAdvances in Anatomy, Embryology and Cell Biology
Antal sidor108
FörlagSpringer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN9783540644941

Tillhör följande kategorier

1 Introduction.- 1.1 Overview.- 1.2 Goals.- 1.3 Scientific Image Computing.- 2 Confocal Imaging of an Acinus.- 2.1 The Imaging Problem in Lung Research.- 2.2 Material and Instrumentation.- 2.3 Prescanning and Definition of a Region of Interest.- 2.4 Confocal Laser Scanning Microscopy.- 2.5 A Framework for Scanning Large Volumes in Confocal 3-D Imaging.- 2.6 A 3-D Data Volume Representing a Complete Acinus.- 3 3-D Analysis of a Complete, Highly Resolved Respiratory Unit.- 3.1 Basics of 3-D Analysis.- 3.2 Image Preprocessing.- 3.3 Segmentation and Labeling.- 3.4 An Automated Segmentation Procedure.- 3.5 Quantification of Structural Components.- 3.6 3-D Topology as an Analytical Tool.- 4 3-D Visualization of Microscopic Volumes of Lung.- 4.1 Basics of 3-D Visualization.- 4.2 Types of Volume Rendering.- 4.3 Voxel Attributes and Object Order Rendering.- 4.4 3-D Imaging Meets 3-D Graphics.- 4.5 Stereoscopic Displays and Virtual Reality.- 5 Discussion of 3-D Analysis at Respiratory Units.- 6 Analysis of the Conductive Part of Lung.- 6.1 Introduction.- 6.2 Stereoscopic Tracings of Casts.- 6.3 Analysis of Traced Data.- 7 A Computer Lung Modeler.- 7.1 Introduction.- 7.2 A Self-Similar, Asymmetric Model of a Lung Lobe.- 7.3 Scaling and Strahler-Ordering Scheme.- 7.4 Transition in the Bifurcation Pattern.- 7.5 Completing a Graphical Lung Model with Limited Stochastics.- 8 Computational Physics Applied to a Bronchial Tree Model.- 8.1 Introduction.- 8.2 Scaling of the Computer Lung Model.- 8.3 Dynamics with Breathing.- 8.4 Convection.- 8.5 Resistance and Reynolds Number.- 8.6 Diffusion.- 8.7 Mass Transport Equations.- 8.8 Implementation and Run-Times.- 9 Model Predictions.- 9.1 Convection and Reynolds Numbers.- 9.2 Oxygen and Ozone Mass Transport.- 10 Discussion of Structural Modeling and Functional Simulation.- 10.1 Summary of Morphological Modeling.- 10.2 How Could the Structure of the Bronchial Tree Be Explained?.- 10.3 Functional Predictions.- 10.4 Outlook.- 11 Summary.- References.

Mer från samma författare

Computational Systems Biology

Kriete, Andres Kriete, Roland Eils, USA) Kriete, Andres (Drexel University, Philadelphia, PA and Coriell Institute for Medical Research, Camden, NJ, Germany) Eils, Roland (Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, and Bioinformatics and Functional Genomics, Institute of Pharmacy and Molecular Biotechnology, University of Heidelberg

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