Evidence-Based Infectious Diseases

Edited by Dr. Dominik Mertz, Associate Professor, Division of Infectious Diseases, McMaster University and Medical Director, Infection Prevention and Control, Hamilton Health Sciences, Hamilton, Ontario, Canada Dr. Fiona Smaill, Professor, Department of Pathology and Molecular Medicine, McMaster University and Medical Microbiologist, Hamilton Regional Laboratory Medicine Program, Hamilton, Ontario, Canada Dr. Nick Daneman, Clinician-Scientist, Division of Infectious Diseases, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada

• List of Contributors viiPreface xi1 Introduction to Evidence‐based Infectious Diseases 1Dominik Mertz, Nick Daneman, and Fiona SmaillPart 1 Specific Diseases 112 Skin and Soft‐tissue Infections 13Douglas Austgarden and Guilio DiDiodato3 Bone and Joint Infections 23Nora Renz and Andrej Trampuz4 Infective Endocarditis 37Bahareh Ghadaki and Deborah Yamamura5 Meningitis and Encephalitis 53Christopher E. Kandel and Wayne L. Gold6 Community‐acquired Pneumonia 73Mark Downing and Jennie Johnstone7 Healthcare‐associated Pneumonia 81Jennie Johnstone and Mark Downing8 Tuberculosis 87Peter Daley and Marek Smieja9 Clostridium Difficile Infection in Adults 99Louis Valiquette10 Urinary Tract Infections 107Thomas Fekete11 Sexually Transmitted Infections 127Courtney A. Thompson, Darrell H. S. Tan, and Kaede Sullivan12 Human Immunodeficiency Virus (HIV) 149Ali Amini, Monique Andersson, Ravindra Gupta, and Brian Angus13 Hepatitis 181Lise Bondy and Michael S. Silverman14 Influenza 193Ashley Roberts and Joanne M. Langley15 Critical Care 201Bram Rochwerg and Jocelyn A. SrigleyPart 2 Special Populations 21516 Infection Prevention and Control 217Graham M. Snyder and Eli N. Perencevich17 Antimicrobial Stewardship 235Alainna J. Jamal and Andrew M. Morris18 Infections in Neutropenic Hosts 251Eric J. Bow19 Infections in General Surgery 269Paul A. Moroz and Christine H. Lee20 Infections in Healthcare Workers 279Gregory W. RoseIndex 287