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In financially constrained health systems across the world, increasing emphasis is being placed on the ability to demonstrate that health care interventions are not only effective, but also cost-effective. This book deals with decision modelling techniques that can be used to estimate the value for money of various interventions including medical devices, surgical procedures, diagnostic technologies, and pharmaceuticals. Particular emphasis is placed on the importance of the appropriate representation of uncertainty in the evaluative process and the implication this uncertainty has for decision making and the need for future research.This highly practical guide takes the reader through the key principles and approaches of modelling techniques. It begins with the basics of constructing different forms of the model, the population of the model with input parameter estimates, analysis of the results, and progression to the holistic view of models as a valuable tool for informing future research exercises. Case studies and exercises are supported with online templates and solutions.This book will help analysts understand the contribution of decision-analytic modelling to the evaluation of health care programmes.ABOUT THE SERIES: Economic evaluation of health interventions is a growing specialist field, and this series of practical handbooks will tackle, in-depth, topics superficially addressed in more general health economics books. Each volume will include illustrative material, case histories and worked examples to encourage the reader to apply the methods discussed, with supporting material provided online. This series is aimed at health economists in academia, the pharmaceutical industry and the health sector, those on advanced health economics courses, and health researchers in associated fields.
Andrew Briggs was appointed to the Lindsay Chair in Health Policy and Economic Evaluation in June 2005. Previously he held the position of Reader in Health Economics at the University of Oxford's Health Economic Research Centre (HERC).Karl Claxton holds an adjunct appointment at Harvard as an Assistant Professor of Health and Decision Sciences. He is part of a committee that appraises new and existing health care technologies and issues guidance for the NHS on the use of these technologies. He has also contributed to the Task Group which developed guidance for the appraisal of health technologies for NICE. He is co-editor of the Journal of Health Economics.Mark Sculpher is Director of the Programme on Economic Evaluation and Health Technology Assessment at the University of York. He has previously worked at the Health Economics Research Group at Brunel University, and in the Department of Clinical Epidemiology and Biostatistics at McMaster University in Canada. He is a member of the NICE Technology Appraisal Committee and he chaired NICE's Task Group on methods guidance for economic evaluation. He is also a member of the Commissioning Board for the NHS Health Technology Assessment programme. He is on the editorial boards of Medical Decision Making, Health Expectations and the Journal of Applied Health Economics and Policy.
1. Introduction ; 2. Key aspects of decision modelling for economic evaluation ; 3. Further developments in decision analytic models for economic evaluation ; 4. Making decision models probabilistic ; 5. Analysing and presenting simulation output from probabilistic models ; 6. Decision-making, uncertainty and the value of information ; 7. Efficient research design ; 8. Future challenges for cost-effectiveness modelling of health care interventions
An advanced, practical guide to the use of probabilistic decision modelling techniques, written by authors at the forfront of developments in this field... Given that NICE recommend the use of probabilistic methods, this book is undoubtedly a welcome handbook for health technology analysts requiring technical details on decision-analytic modelling.
Roger Wagner, Andrew Briggs, Artist and writer) Wagner, Roger (Artist and writer, UK) Briggs, Andrew (Professor of Nanomaterials, Professor of Nanomaterials, University of Oxford
Andrew Briggs, Hans Halvorson, Andrew Steane, UK) Briggs, Andrew (Professor of Nanomaterials, Professor of Nanomaterials, University of Oxford, USA) Halvorson, Hans (Stuart Professor of Philosophy, Stuart Professor of Philosophy, Princeton University, UK) Steane, Andrew (University Lecturer and Fellow, University Lecturer and Fellow, Exeter College, University of Oxford, Andrew, Briggs
Roger Wagner, Andrew Briggs, Artist and writer) Wagner, Roger (Artist and writer, UK) Briggs, Andrew (Professor of Nanomaterials, Professor of Nanomaterials, University of Oxford
Andrew Briggs, Michael J. Reiss, University of Oxford) Briggs, Andrew (Professor of Nanomaterials, Department of Materials, University College of London) Reiss, Michael J. (Professor of Science Education
Andrew Briggs, Oleg Kolosov, University of Oxford) Briggs, Andrew (Department of Materials, University of Lancaster) Kolosov, Oleg (Department of Physics, KOLOSOV BRIGGS, Kolosov Briggs
David Bishai, Logan Brenzel, William Padula, United States) Bishai, David (Professor (adjunct), Professor (adjunct), Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Bill & Melinda Gates Foundation) Brenzel, Logan (Senior Program Officer, Senior Program Officer, University of Southern California (USC)) Padula, William (Assistant Professor; Fellow, Assistant Professor; Fellow, Department of Pharmaceutical & Health Economics, School of Pharmacy; Leonard D. Schaeffer Center for Health Policy and Economics
Rhiannon Tudor Edwards, Emma McIntosh, UK) Tudor Edwards, Rhiannon (Professor of Health Economics, Professor of Health Economics, Centre for Health Economics and Medicines Evaluations, Bangor University, Wales, UK) McIntosh, Emma (Professor of Health Economics, Professor of Health Economics, Health Economics and Health Technology Assessment, (HEHTA), University of Glasgow, Emma Mcintosh
Richard Cookson, Richard Cookson, Susan Griffin, Ole F. Norheim, Anthony J. Culyer, UK) Cookson, Richard (Professor, Professor, Centre for Health Economics, University of York, UK) Griffin, Susan (Senior Research Fellow, Senior Research Fellow, Centre for Health Economics, University of York, Norway) Norheim, Ole F. (Professor, Professor, Department of Global Public Health, University of Bergen, UK) Culyer, Anthony J. (Professor Emeritus, Professor Emeritus, University of York, Ole F Norheim, Anthony J Culyer
Alastair M. Gray, Philip M. Clarke, Jane L. Wolstenholme, Sarah Wordsworth, UK) Gray, Alastair M. (Professor of Health Economics and Director of the Health Economics Research Centre, Department of Public Health, University of Oxford, Australia) Clarke, Philip M. (Associate Professor, Sydney School of Public Health, The University of Sydney, UK) Wolstenholme, Jane L. (Senior Research Officer, Health Economics Research Centre, Department of Public Health, University of Oxford, UK) Wordsworth, Sarah (Senior Research Fellow, Health Economics Research Centre, Department of Public Health, University of Oxford, Alistair M. Gray
Emma Mcintosh, Philip Clarke, Emma J Frew, Emma McIntosh, Philip Clarke, Emma Frew, Jordan Louviere, UK) McIntosh, Emma (Health Economics Research Centre, Department of Public Health, University of Oxford, Australia) Clarke, Philip (The University of Sydney, UK) Frew, Emma (Senior Lecturer in Health Economics, University of Birmingham, Australia) Louviere, Jordan (Professor of Marketing and Executive Director, Centre for the Study of Choice (CenSoC), The University of Technology, Sydney
Henry A. Glick, Jalpa A. Doshi, Seema S. Sonnad, Daniel Polsky, USA) Sonnad, Seema S. (, Director of Health Services Research, The Value Institute, Christiana Care Health System, USA; Adjunct Associate Professor, Department of Surgery, Perelam School of Medicine, Adjunct Senior Fellow, Leonard Davis Institute of Health Economics, University of Pennsylvania, USA) Polsky, Daniel (, Robert D. Eilers Professor, Health Care Management, The Wharton School; Professor of Medicine, Division of General Internal Medicine, Perelam School of Medicine; Executive Director, Leonard Davis Institute of Health Economics; University of Pennsylvania
Alastair M. Gray, Philip M. Clarke, Jane L. Wolstenholme, Sarah Wordsworth, UK) Gray, Alastair M. (Professor of Health Economics and Director of the Health Economics Research Centre, Department of Public Health, University of Oxford, Australia) Clarke, Philip M. (Associate Professor, Sydney School of Public Health, The University of Sydney, UK) Wolstenholme, Jane L. (Senior Research Officer, Health Economics Research Centre, Department of Public Health, University of Oxford, UK) Wordsworth, Sarah (Senior Research Fellow, Health Economics Research Centre, Department of Public Health, University of Oxford, Alistair M. Gray
Rhiannon Tudor Edwards, Emma McIntosh, UK) Tudor Edwards, Rhiannon (Professor of Health Economics, Professor of Health Economics, Centre for Health Economics and Medicines Evaluations, Bangor University, Wales, UK) McIntosh, Emma (Professor of Health Economics, Professor of Health Economics, Health Economics and Health Technology Assessment, (HEHTA), University of Glasgow, Emma Mcintosh
Emma Mcintosh, Philip Clarke, Emma J Frew, Emma McIntosh, Philip Clarke, Emma Frew, Jordan Louviere, UK) McIntosh, Emma (Health Economics Research Centre, Department of Public Health, University of Oxford, Australia) Clarke, Philip (The University of Sydney, UK) Frew, Emma (Senior Lecturer in Health Economics, University of Birmingham, Australia) Louviere, Jordan (Professor of Marketing and Executive Director, Centre for the Study of Choice (CenSoC), The University of Technology, Sydney
Richard Cookson, Richard Cookson, Susan Griffin, Ole F. Norheim, Anthony J. Culyer, UK) Cookson, Richard (Professor, Professor, Centre for Health Economics, University of York, UK) Griffin, Susan (Senior Research Fellow, Senior Research Fellow, Centre for Health Economics, University of York, Norway) Norheim, Ole F. (Professor, Professor, Department of Global Public Health, University of Bergen, UK) Culyer, Anthony J. (Professor Emeritus, Professor Emeritus, University of York, Ole F Norheim, Anthony J Culyer
Henry A. Glick, Jalpa A. Doshi, Seema S. Sonnad, Daniel Polsky, USA) Sonnad, Seema S. (, Director of Health Services Research, The Value Institute, Christiana Care Health System, USA; Adjunct Associate Professor, Department of Surgery, Perelam School of Medicine, Adjunct Senior Fellow, Leonard Davis Institute of Health Economics, University of Pennsylvania, USA) Polsky, Daniel (, Robert D. Eilers Professor, Health Care Management, The Wharton School; Professor of Medicine, Division of General Internal Medicine, Perelam School of Medicine; Executive Director, Leonard Davis Institute of Health Economics; University of Pennsylvania
David Bishai, Logan Brenzel, William Padula, United States) Bishai, David (Professor (adjunct), Professor (adjunct), Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Bill & Melinda Gates Foundation) Brenzel, Logan (Senior Program Officer, Senior Program Officer, University of Southern California (USC)) Padula, William (Assistant Professor; Fellow, Assistant Professor; Fellow, Department of Pharmaceutical & Health Economics, School of Pharmacy; Leonard D. Schaeffer Center for Health Policy and Economics
Revill Paul, REVILL PAUL, Paul Revill, Marc Suhrcke, Rodrigo Moreno-serra, Mark Sculpher, Uk) Revill, Paul (Univ Of York, Uk) Suhrcke, Marc (Univ Of York, Uk) Moreno-serra, Rodrigo (Univ Of York, Uk) Sculpher, Mark (Univ Of York