Concerted Organic and Bio-Organic Mechanisms

• DEFINITIONS, Origin of the Concept, Mechanism and its Description, The Definition of Concertedness, Bond Order and Coupling, Potential energy or Free Energy?, Classes of Concerted Reactions, TECHNIQUES, Detection of Intermediates, Exclusion of Stepwise Mechanisms, Transition State Structure, PROTON TRANSFER, Proton Transfer between Bases, Proton Transfer and Displacement Reactions at Saturated Carbon Centers, Proton Transfer and Double Bond Changes, Non-Perfect Synchronization, NUCLEOPHILIC DISPLACEMENTS AT UNSATURATED CARBON, Displacements at the Carbonyl Group, Vinyl Group Transfer, Nucleophilic Aromatic Substitution, Nucleophilic Substitution at Diagonal Carbon, NUCLEOPHILIC DISPLACEMENTS AT SATURATED CARBON, Mechanisms, The Carbenium Ion, Ion-Pair Intermediates, The Concerted Mechanism, DISPLACEMENT REACTIONS AT HETEROATOMS, Electophilic Displacement at Hydrogen, Nucleophilic Displacement at Saturated Nitrogen, Nucleophilc Displacement at Silicon, Nuleophilic Displacement at Phosphorus(V), Displacement at Sulfur, CYCLIC REACTIONS, Intermediates, Clock Reactions, Energetic Relationships, Nascent Products, Isotope Effects, Theoretical Methods, ENZYME REACTIONS, Proton Transfer, Theoretical Calculations, Isotopes, Carbohydrases, Aspartyl Proteases, Hydride Transfer, Amine Oxidases, Carbon-Carbon Bond Formation, Clocks, Cyclic Reactions

"This is an excellent and authoritative book that covers not only concerted reactions but also stepwise reactions originally posed to be concerted. The book is very densely written, with much information, and with a careful reasoning style that demands concentration from the reader…offers a concise guide to a wide range of mechanistic studies. It will reward the careful student or researcher."--Charles L. Perrin, University of California, San Diego, American Chemical Society Journal