Sometimes, with great luck, you happen on a book that is wondrous in its ability to take a topic apart and explain it lucidly. Sometimes, the joy is to be found in the way an author is able to put those pieces back together. And sometimes, it is the elegance both of analysis and synthesis that makes a book truly great. The Century of the Gene, by Evelyn Fox Keller, reaches that level and then vaults past it into the category of rare volumes that are unforgettable. This is the sort of book that, once found, can never be relinquished. The breadth of intellect is so strong, the importance of the subject so acute, the language so beautifully wrought, that you find yourself drawn to read it again and again, only to find a new dimension each time… In fact—and this is one of the most intense pleasures of the book—Fox Keller’s explanation of how the thinking about the gene has evolved over the past century is both as simple and as complex as the gene itself. Her topic is also her metaphor.