Atomic Force Microscopy for Nanoscale Biophysics

From Single Molecules to Living Cells

Häftad, Engelska, 2023

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Atomic Force Microscopy for Nanoscale Biophysics: From Single Molecules to Living Cells summarizes the applications of atomic force microscopy for the investigation of biomolecules and cells. The book discusses the methodology of AFM-based biomedical detection, diverse biological systems, and the combination of AFM with other complementary techniques. These state-of-the-art chapters empower researchers to address biological issues through the application of atomic force microscopy. Atomic force microscopy (AFM) is a unique, multifunctional tool for investigating the structures and properties of living biological systems under aqueous conditions with unprecedented spatiotemporal resolution.

Summarizes the recent progress of atomic force microscopy in biomedical applications
Presents the methods and skills of applying atomic force microscopy
Aids researchers in investigating the nanoscale biophysics of diverse biological systems

Produktinformation

Utgivningsdatum2023-02-22
Mått152 x 229 x undefined mm
Vikt630 g
FormatHäftad
SpråkEngelska
Antal sidor336
FörlagElsevier Science
ISBN9780323953603

Tillhör följande kategorier

Tillämpad fysik inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik
Cellbiologi inom Naturvetenskap och teknik

Mi Li PhD is a Full Professor at Shenyang Institute of Automation Chinese Academy of Sciences, Shenyang, China. Mi Li received the Ph.D. degree in 2015 from Shenyang Institute of Automation (SIA) Chinese Academy of Sciences, Shenyang, China, after which he continues academic career at SIA until now. Since 2009, Mi Li has been engaged in the studies of atomic force microscopy (AFM) and its biomedical applications ranging from molecules and organelles to cells as well as hydrogels, to reveal the role of micro/nanoscale biophysical cues in regulating life activities. Mi Li has conducted long-term visitor studies at The Ohio State University, Columbus, USA and ETH Zurich, Switzerland, respectively for academic research regarding AFM. Mi Li has won the National Natural Science Foundation of China for Excellent Young Scholars (2019), the IEEE Senior Member (2020), the Outstanding Doctoral Dissertation Award of Chinese Academy of Sciences (2016) and the Springer Theses (2018).

1. Fundamentals and methods of AFM for biophysics2. Imaging and force detection of DNA by AFM3. High-resolution imaging and force spectroscopy of membrane proteins by AFM4. Characterizing the nanostructures and properties of hydrogels by AFM5. Detecting the behaviours of single virus by AFM6. Nanoscale imaging and force probing of single microbial cells by AFM7. Investigating the structures and mechanics of single animal cells by AFM8. Combining AFM with complementary techniques: Hybrid AFM for biophysics9. Conclusion and future perspectives