Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment

Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment, National Research Council

• 1 Front Matter; 2 Summary; 3 1 Introduction; 4 2 Toxicogenomic Technologies; 5 3 Experimental Design and Data Analysis; 6 4 Application to Exposure Assessment; 7 5 Application to Hazard Screening; 8 6 Application to Analyzing Variation in Human Susceptibility; 9 7 Application to the Study of Mechanisms of Action; 10 8 Other Potential Applications of Toxicogenomic Technologies to Risk Assessment; 11 9 Validation; 12 10 Sample and Data Collection and Analysis; 13 11 Ethical, Legal, and Social Issues; 14 12 Conclusions and Recommendations; 15 References; 16 Appendix A: Biographic Information on the Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology; 17 Appendix B: Minimum Information About a Microarray Experiment for Toxicogenomics; 18 Appendix C: Overview of Risk Assessment