The vaccine used to protect humans against the anthrax disease, called Anthrax Vaccine Adsorbed (AVA), was licensed in 1970. It was initially used to protect people who might be exposed to anthrax where they worked, such as veterinarians and textile plant workers who process animal hair. When the U. S. military began to administer the vaccine, then extended a plan for the mandatory vaccination of all U. S. service members, some raised concerns about the safety and efficacy of AVA and the manufacture of the vaccine. In response to these and other concerns, Congress directed the Department of Defense to support an independent examination of AVA. The Anthrax Vaccine: Is It Safe? Does It Work? reports the studya (TM)s conclusion that the vaccine is acceptably safe and effective in protecting humans against anthrax. The book also includes a description of advances needed in main areas: improving the way the vaccine is now used, expanding surveillance efforts to detect side effects from its use, and developing a better vaccine.
Lois M. Joellenbeck, Lee L. Zwanziger, Jane S. Durch, and Brian L. Strom, Editors, Committee to Assess the Safety and Efficacy of the Anthrax Vaccine, Medical Follow-Up Agency
1 Front Matter; 2 Executive Summary; 3 1 Introduction; 4 2 Background; 5 3 Anthrax Vaccine Efficacy; 6 4 Safety: Introduction; 7 5 Safety: Case Reports; 8 6 Safety: Epidemiologic Studies; 9 7 Anthrax Vaccine Manufacture; 10 8 Future Needs; 11 Appendix A Statement of Task; 12 Appendix B Biographical Sketches; 13 Appendix C Information-Gathering Meeting Agendas; 14 Appendix D Anthrax Vaccine Adsorbed Package Inserts; 15 Appendix E Vaccine Adverse Event Reporting System (VAERS) Form; 16 Appendix F Anthrax Vaccine Expert Committee (AVEC) Case Assessment Form; 17 Appendix G DMSS Analyses Requested by the IOM Committee to Assess the Safety and Efficacy of the Anthrax Vaccine; 18 Appendix H An Assessment of the Safety of the Anthrax Vaccine: A Letter Report
National Research Council, Division of Behavioral and Social Sciences and Education, Institute of Medicine, and Families Board on Children, Youth, Steve Olson
Institute of Medicine, Board on the Health of Select Populations, and Transgender Health Issues and Research Gaps and Opportunities Committee on Lesbian, Gay, Bisexual
Institute of Medicine, Board on Population Health and Public Health Practice, Division of Health Promotion and Disease Prevention, Division of International Health
Institute of Medicine, Committee to Develop Methods Useful to the Department of Veteran Affairs in Estimating Its Physician Requirements, Joseph Lipscomb
Institute of Medicine, Medical Follow-up Agency, Committee on Noise-Induced Hearing Loss and Tinnitus Associated with Military Service from World War II to the Present, Jane S. Durch, Lois M. Joellenbeck, Larry E. Humes
National Research Council, Institute of Medicine, Board on Life Sciences, Medical Follow-up Agency, and Acquisition of Medical Countermeasures Against Biological Warfare Agents Committee on Accelerating the Research, Development, Leslie Z. Benet, Jane S. Durch, Lois M. Joellenbeck
Institute of Medicine, Division of Health Promotion and Disease Prevention, Committee to Study Priorities for Vaccine Development, Robert S. Lawrence, Jane S. Durch, Kathleen R. Stratton
National Research Council, Division of Behavioral and Social Sciences and Education, Commission on Behavioral and Social Sciences and Education, Panel on Performance Measures and Data for Public Health Performance Partnership Grants, Susan M. Skillman, Jane S. Durch, Edward B. Perrin
Institute of Medicine, Medical Follow-up Agency, Committee to Study the Mortality of Military Personnel Present at Atmospheric Tests of Nuclear Weapons, Heather O'Maonaigh, Harriet Crawford, William F. Page, Susan Thaul