Adult Acute Lymphocytic Leukemia

• A Perspective on the Treatment of Acute Lymphoblastic Leukemia.- Clinical Features and Making the Diagnosis.- The Biology of Adult Acute Lymphoblastic Leukemia.- Minimal Residual Disease in Acute Lymphoblastic Leukemia.- Cytogenetics.- Acute Lymphoblastic leukemia: Epidemiology.- Prognostic Factors in Acute Lymphoblastic Leukemia.- The Generalized Care of the Patient with Acute Lymphoblastic Leukemia.- Treatment of Acute Lymphoblastic Leukemia in Middle-Age and Older Adults.-Pharmacology of Acute Lymphoblastic Leukemia Therapy.- Assessment of Response to Treatment.- T-cell Acute Lymphoblastic Leukemia.- Burkitt Leukemia and Lymphoma.- Treatment of Acute Lymphoblastic Leukemia in Young AdultsNicolas Boissel.- Treatment of Philadephia Chromosome Positive Acute Lymphoblastic Leukemia.- Molecular Therapies.- Treatment of Relapsed/ Refractory Acute Lymphoblastic Leukemia.- Allogenic Stem Cell Transplantation for Acute Lymphoblastic Leukemia in Adults.- Hematopoietic Stem Cell Transplantation in Philadelphia-positive Acute Lymphoblastic Leukemia.- Special Challenges: Genetic polymorphisms and therapy.- Late Consequences of Therapy of Acute Lymphoblastic Leukemia.- Immunotherapy for Acute Lymphocytic Leukemia.- Unique Subtypes in Acute Lymphoblastic Leukemia.

From the reviews:“The focus of this book is on acute lymphocytic leukemia in adults, with frequent allusions to the childhood form of disease. … the only recent text solely focused on acute lymphocytic leukemia as it relates to subtypes of disease in each of the adult age groups. It is up to date and well referenced, and it integrates basic, translational, and clinical science. As such it serves as a unique resource for scientists and clinicians in the field of acute lymphocytic leukemia.” (Paulette Mehta, Journal of the American Medical Association, June, 2011)“Twenty-three chapters cover a range of clinically biased topics, from diagnosis and epidemiology to assessment of response to therapy, salvage protocols and the late effects of successful therapy. The text is broken up by tables, graphs and occasional colour illustrations, while extensive lists of references supplement each chapter. … A section on the biology of ALL helps to explain the diversity and underlying genetic instability of the disease. … this collection of reviews will prove to be a very useful supplementary reference text.” (Maria H. Gilleece, Bulletin of the Royal College of Pathologists, April, 2012)