Year Book of Dermatology 2019

Shashi Kumar BM MD (DVL) FIADVL (Dermatopath)Associate Professor, Department of Dermatology, Mandya Institute of Medical Sciences, Mandya, Karnataka, IndiaSavitha AS MD (DVL) DNB FRGUHS (Dermatosurgery)Associate Professor, Department of Dermatology, Sapthagiri Institute of Medical Science and Research Centre, Bengaluru, Karnataka, IndiaR Raghunatha Reddy MD (DVL) DNB FRGUHS (Dermatosurgery)Professor and Head, Department of Dermatology, Akash Institute of Medical Sciences and Research Centre, Bengaluru, Karnataka, India

• 1. Treatment of Moderate Acne Vulgaris in Fitzpatrick Skin Type V or VI: Efficacy and Tolerability of Fixed Combination Clindamycin Phosphate 1.2%/Benzoyl Peroxide 3.75% Gel2. Novel Tretinoin 0.05% Lotion for the Once-daily Treatment of Moderate-to-severe Acne Vulgaris: Assessment of Efficacy and Safety in Patients aged 9 Years and Older3. Once-daily Oral Sarecycline 1.5 mg/kg/day is Effective for Moderate-to-severe Acne Vulgaris: Results from Two Identically Designed, Phase 3, Randomized, Double-blind Clinical Trials4. The Efficacy and Safety of Azelaic Acid 15% Foam in the Treatment of Facial Acne Vulgaris5. Frequency of Treatment Switching for Spironolactone Compared to Oral Tetracycline-class Antibiotics for Women with Acne: A Retrospective Cohort Study 2010–20166. Clinical Experience with Once-daily Dapsone Gel, 7.5% Monotherapy in Patients with Acne Vulgaris7. An Acne Survey from the World's Largest Annual Gathering of Twins8. Efficacy and Safety of Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel plus Oral Doxycycline in Subjects with Severe Inflammatory Acne who are Candidates for Oral Isotretinoin9. Efficacy, Safety and Tolerability of Topical Dapsone Gel, 7.5% for Treatment of Acne Vulgaris by Fitzpatrick Skin Phototype10. Clinical Significance of Neutrophil Gelatinase-associated Lipocalin and Galectin-7 in Tape-stripped Stratum Corneum of Acne Vulgaris11. Risk of Depression among Patients with Acne: A Population-based Cohort Study using The Health Improvement Network (THIN) Database12. Acne Development in Male Androgenetic Alopecia13. Effects of Isotretinoin Treatment on Affective and Cognitive Functions in Adolescent Acne Vulgaris Patients14. Analysis of Gut Microbiome in Patients with Acne Vulgaris15. Isotretinoin Therapy: A Retrospective Cohort Analysis of Completion Rates and Factors Associated with Nonadherence16. Photodynamic Therapy for Acne Conglobata of the Buttocks: Effective Anti-inflammatory Treatment with Good Cosmetic Outcome17. Acneiform Eruptions: An Unusual Dermatological Side Effect of Ribavirin18. Topical Dapsone Gel is a New Treatment Option for Acne Agminata19. The Effect of Continuous High versus Low Dose Oral Isotretinoin Regimens on Dermcidin Expression in Patients with Moderate-to-severe Acne Vulgaris20. Transgender Adolescents and Acne: A Case Series21. Chemical Peels in the Treatment of Acne: Patient Selection and Perspectives22. A Novel Cognitive Stress Management Technique for Acne Vulgaris: A Short Report of a Pilot Experimental Study23. Evaluation of the Efficacy of Microneedle Fractional Radiofrequency in Turkish Patients with Atrophic Facial Acne Scars24. Effect of Oral Isotretinoin on the Nucleocytoplasmic Distribution of FoxO1 and FoxO3 Proteins in Sebaceous Glands of Patients with Acne Vulgaris25. Adult-onset Acne: Prevalence, Impact and Management Challenges26. Acne: A Side Effect of Masculinizing Hormonal Therapy in Transgender Patients27. Efficacy and Safety Profile of Spironolactone 50 mg v/s Isotretinoin 10 mg in the Treatment of Female Patients with Acne Vulgaris Grade 1-2—A Double Blinded, Randomized Comparative Study28. The Microbiome in Preadolescent Acne: Assessment and Prospective Analysis of the Influence of Benzoyl Peroxide29. Association of Systemic Antibiotic Treatment of Acne with Skin Microbiota Characteristics30. Novel Nicotinamide Skin-adhesive Hot Melt Extrudates for Treatment of Acne31. Treatment of Acne with a Combination of Propolis, Tea Tree Oil and Aloe vera Compared to Erythromycin Cream: Two Double-blind Investigations32. The Safety and Efficacy of Four Different Fixed Combination Regimens of Adapalene 0.1%/Benzoyl Peroxide 2.5% Gel for the Treatment of Acne Vulgaris: Results from a Randomized Controlled Study33. Survey of Acne-related Post-inflammatory Hyperpigmentation in the Middle East34. The Use of Hormonal Antiandrogen Therapy in Female Patients with Acne: A 10-year Retrospective Study35. Adapalene 0.3% Gel Shows Efficacy for the Treatment of Atrophic Acne Scars36. Evaluation the Efficacy of Trichloroacetic Acid 33% in Treatment of Oral Retinoid-induced Cheilitis Compared with Placebo (Vaseline): A Randomized Pilot Study37. Light Therapies for Acne: Abridged Cochrane Systematic Review including GRADE Assessments38. Dapsone-loaded Invasomes as a Potential Treatment of Acne: Preparation, Characterization and In Vivo Skin Deposition Assay39. Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-month Randomized, Vehicle-controlled Trial using Intra-individual Comparison40. Complementary and Alternative Methods for Treatment of Acne Vulgaris: A Systematic Review41. Effects of the Myrtle Essential Oil on the Acne Skin—Clinical Trials for Korean Women42. Comparison of Efficacy of Commercially Available versus Freshly Prepared Salicylic Acid Peel in Treatment of Acne: A Randomized Open-label Study43. A Comparison of Combined Oral Contraceptives Containing Chlormadinone Acetate versus Drospirenone for the Treatment of Acne and Dysmenorrhea: A Randomized Trial44. Efficacy and Adverse Events of Oral Isotretinoin for Acne: A Systematic Review45. Aromatherapy, Botanicals, and Essential Oils in Acne46. A Review of Diagnosis and Treatment of Acne in Adult Female Patients47. Clinical Evidence for Washing and Cleansers in Acne Vulgaris: A Systematic Review48. ROS-responsive Microneedle Patch for Acne Vulgaris Treatment49. Optimizing the Use of Topical Retinoids in Asian Acne Patients50. Comparative Study of the Efficacy of Platelet-rich Plasma Combined with Carboxytherapy versus its Use with Fractional Carbon Dioxide Laser in Atrophic Acne Scars51. Effects of Oral Supplementation with FOS and GOS Prebiotics in Women with Adult Acne: The “SO Sweet” Study: A Proof-of-concept Pilot Trial52. Approaches to Limit Systemic Antibiotic Use in Acne: Systemic Alternatives, Emerging Topical Therapies, Dietary Modification, and Laser and Light-based Treatments53. The Efficacy and Tolerability of 5-aminolevulinic Acid 5% Thermosetting Gel Photodynamic Therapy in the Treatment of Mild-to-moderate Acne Vulgaris. A Two-center, Prospective Assessor-blinded, Proof-of-concept Study54. Combination Chemical Peels are More Effective than Single Chemical Peel in Treatment of Mild-to-moderate Acne Vulgaris: A Split Face Comparative Clinical Trial55. Comparison of Efficacy of Aminolevulinic Acid Photodynamic Therapy versus Adapalene Gel plus Oral Doxycycline for Treatment of Moderate Acne Vulgaris – A Simple, Blind, Randomized, and Controlled Trial56. Microneedling by Dermapen and Glycolic Acid Peel for the Treatment of Acne Scars: Comparative Study57. Antipruritic Efficacies of Doxycycline and Erythromycin in the Treatment of Acne Vulgaris: A Randomized Single-blinded Pilot Study58. Does Isotretinoin Cause Depression and Anxiety in Acne Patients?59. Treatment of Atrophic Acne Scarring with Fractional Micro-plasma Radiofrequency in Chinese Patients: A Prospective Study60. Comparison of Novel Dual Mode versus Conventional Single Pass of a 1450-nm Diode Laser in the Treatment of Acne Vulgaris for Korean Patients: A 20-week Prospective, Randomized, Split-face Study61. Resurfacing of Facial Acne Scars with a New Variable-pulsed Er:YAG Laser in Fitzpatrick Skin Types IV and V62. A Novel Topical Minocycline Foam for the Treatment of Moderate-to-severe Acne Vulgaris: Results of 2 Randomized, Double-blind, Phase 3 Studies63. Management of Comedonal Acne Vulgaris with Fixed-combination Topical Therapy64. Blunt Cannula Subcision is more Effective than Nokor Needle Subcision for Acne Scars Treatment65. Novel Tretinoin 0.05% Lotion for the Once-daily Treatment of Moderate-to-severe Acne Vulgaris in a Preadolescent Population66. Efficacy of Two Plant Extracts Against Acne Vulgaris: Initial Results of Microbiological Tests and Cell Culture Studies67. Female Type of Adult Acne: Physiological and Psychological Considerations and Management68. The Efficacy and Safety of Nonpharmacological Therapies for the Treatment of Acne Vulgaris: A Systematic Review and Best-evidence Synthesis69. Clindamycin Phosphate 1.2%/Benzoyl Peroxide 3% Fixed-dose Combination Gel versus Topical Combination Therapy of Adapalene 0.1% Gel and Clindamycin Phosphate 1.2% Gel in the Treatment of Acne Vulgaris in Japanese Patients: A Multicenter, Randomized, Investigator-blind, Parallel-group Study70. Screening of Body Dysmorphic Disorder in Acne Patients: A Pilot Study71. A Qualitative Investigation of the Impact of Acne on Health-related Quality of Life: Development of a Conceptual Model72. Host-microbiome Interactions and Recent Progress into Understanding the Biology of Acne Vulgaris73. Acne in Lom©, Togo: Clinical Aspects and Quality of Life of Patients74. The Role of the Physician in Patient Perceptions of Barriers to Primary Adherence with Acne Medications75. Exploring the Relationship between Stress and Acne: A Medical Student’s Perspective76. The Impact of Acne and Facial Postinflammatory Hyperpigmentation on Quality of Life and Self-esteem of Newly Admitted Nigerian Undergraduates77. Which Acne Treatment has the Best Influence on Health-related Quality of Life? Literature Review by the European Academy of Dermatology and Venereology Task Force on Quality of Life and Patient Oriented Outcomes78. Stressful Life Events and Psychiatric Comorbidity in Acne–A Case Control Study79. The Evaluation of Psychiatric Comorbidity, Self-injurious Behavior, Suicide Probability, and other Associated Psychiatric Factors (Loneliness, Self-esteem, Life Satisfaction) in Adolescents with Acne: A Clinical Pilot Study80. Acne Relapses: Impact on Quality of Life and Productivity81. The Mental Health Burden in Acne Vulgaris and Rosacea: An Analysis of the US National Inpatient Sample82. The Therapeutic Effect of Tanshinone IIA on Propionibacterium acnes-induced Inflammation In Vitro83. Anti-acne Properties of Hydrophobic Fraction of Red Ginseng (Panax Ginseng C.A. Meyer) and its Active Components84. Mechanistic Insight into the Activity of a Sulfone Compound Dapsone on Propionibacterium (Newly Reclassified as Cutibacterium) Acne's–mediated Cytokine Production85. Lipidomics Reveals Skin Surface Lipid Abnormity in Male Youth Acne86. Acne Vulgaris Severity Graded by In Vivo Reflectance Confocal Microscopy and Optical Coherence Tomography87. Vitamin D Levels in Acne Vulgaris Patients Treated with Oral Isotretinoin88. The Effect of Milk Consumption on Acne: A Meta-analysis of Observational Studies89. Acne and Nutrition: Hypotheses, Myths and Facts90. Enhancement of Lipid Content and Inflammatory Cytokine Secretion in SZ95 Sebocytes by Palmitic Acid Suggests a Potential Link between Free Fatty Acids and Acne Aggravation91. Characterization of Cutibacterium acnes Phylotypes in Acne and In Vivo Exploratory Evaluation of Myrtacine92. Atrophic Scar Formation in Acne Patients involves Long-acting Immune Responses with Plasma Cells and Alteration of Sebaceous Gland93. Lesional and Circulating Levels of Interleukin 17 and 25 Hydroxy-cholecalciferol in Active Acne Vulgaris: Correlation to Disease Severity94. Clinical Efficacy of 0.5% Topical Mangosteen Extract in Nanoparticle Loaded Gel in Treatment of Mild?to?moderate Acne Vulgaris: A 12-Week, Split-Face, Double-blinded, Randomized, Controlled Trial95. The Influence of Exposome on Acne96. Association of Interleukin-6 Gene Promoter Polymorphism with Acne Vulgaris and its Severity97. Genome-wide Meta-analysis Implicates Mediators of Hair Follicle Development and Morphogenesis in Risk for Severe Acne98. Microbiological Profile of Sarecycline: A Novel Targeted Spectrum Tetracycline for the Treatment of Acne Vulgaris99. Daily Intake of Soft Drinks and Moderate-to-severe Acne Vulgaris in Chinese Adolescents100. New Concepts, Concerns, and Creations in Acne101. The Anti-inflammatory Activities of Propionibacterium acnes CAMP Factor-targeted Acne Vaccines102. Skin Ecology during Sebaceous Drought—How Skin Microbes Respond to Isotretinoin103. Propionibacterium acnes-derived Extracellular Vesicles Promote Acne-like Phenotypes in Human Epidermis104. Patients with Acne Vulgaris have a Distinct Gut Microbiota in Comparison with Healthy Controls105. Inhibitory Effects of Euphorbia supina on Propionibacterium acnes-induced Skin Inflammation In Vitro and In Vivo106. Isolation and Identification of the Follicular Microbiome: Implications for Acne Research107. Expression of Inflammatory and Fibrogenetic Markers in Acne Hypertrophic Scar Formation: Focusing on Role of TGF- and IGF-1R108. Decrease in Diversity of Propionibacterium acnes Phylotypes in Patients with Severe Acne on the Back109. Short Lipopeptides Specifically Inhibit the Growth of Propionibacterium acnes with Antibacterial and Anti-inflammatory Dual Action110. Plasma Exeresis for Active Acne Vulgaris: Clinical and In Vivo Microscopic Documentation of Treatment Efficacy by Means of Reflectance Confocal Microscopy111. Licochalcone A Attenuates Acne Symptoms Mediated by Suppression of NLRP3 Inflammasome112. Gut Microbiota Alterations in Moderate-to-severe Acne Vulgaris Patients113. Overall and Subgroup Prevalence of Acne Vulgaris among Patients with Hidradenitis Suppurativa114. Association of the TNF- Gene Promoter Polymorphisms at Nucleotide-238 and -308 with Acne Susceptibility: A Meta-analysis115. Tumor Necrosis Factor a-308 G/A and Interleukin 1 b-511 C/T Gene Polymorphisms in Patients with Scarring Acne116. SIG1459: A Novel Phytyl-Cysteine Derived TLR2 Modulator with In Vitro and Clinical Anti-acne Activity117. Associations among Two Vitamin D Receptor (VDR) Gene Polymorphisms (ApaI and TaqI) in Acne Vulgaris: A Pilot Susceptibility Study118. Using Network Oriented Research Assistant (NORA) Technology to Compare Digital Photographic with In-Person Assessment of Acne Vulgaris119. Genetic Association between the NLRP3 Gene and Acne Vulgaris in a Chinese Population120. Serum Irisin: A Prognostic Marker for Severe Acne Vulgaris121. Primary Sebocytes and Sebaceous Gland Cell Lines for Studying Sebaceous Lipogenesis and Sebaceous Gland Diseases122. Acne Vulgaris in Patients with Hidradenitis Suppurativa123. Validation of 3D Skin Imaging for Objective Repeatable Quantification of Severity of Atrophic Acne Scarring124. No Evidence for Follicular Keratinocyte Hyperproliferation in Acne Lesions as Compared to Autologous Healthy Hair Follicles125. Seasonal Changes in Epidermal Ceramides are Linked to Impaired Barrier Function in Acne Patients126. Cutibacterium acnes (Propionibacterium acnes) and Acne Vulgaris: A Brief Look at the Latest Updates127. The In Vitro Antimicrobial Evaluation of Commercial Essential Oils and their Combinations against Acne128. Seasonal Aggravation of Acne in Summers and the Effect of Temperature and Humidity in a Study in a Tropical Setting129. Acne Prevalence in 9–14-year old Patients Attending Pediatric Ambulatory Clinics in Italy130. Confocal Microscopy in Adult Women with Acne131. Erythema-directed Digital Photography for the Enhanced Evaluation of Topical Treatments for Acne Vulgaris132. Acne Vulgaris: The Metabolic Syndrome of the Pilosebaceous Follicle133. Circular RNA Expression Profile Analysis of Severe Acne by RNA-Seq and Bioinformatics134. Taxonomy and Phylogeny of Cutibacterium (formerly Propionibacterium) Acnes in Inflammatory Skin Diseases135. Transforming Acne Care by Pediatricians: An Interventional Cohort Study