Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease

Inbunden, Engelska, 2023

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The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation.

Produktinformation

Utgivningsdatum2023-08-01
Mått155 x 235 x 23 mm
Vikt718 g
FormatInbunden
SpråkEngelska
SerieHandbook of Experimental Pharmacology
Antal sidor316
FörlagSpringer International Publishing AG
ISBN9783031384363

Tillhör följande kategorier

Preface.- Part 1 Modulation.- Cav1.1Calcium Channel Signaling Complexes in Excitation–Contraction Coupling: Insights from Channelopathies.- Mechanisms of Vascular CaV1.2 Channel Regulation During Diabetic Hyperglycemia.- Sympathetic Nervous System Regulation of Cardiac Calcium Channels.- Modulation of CaV1.2 Channel Function by Interacting Proteins and Post-Translational Modifications: Implications in Cardiovascular Diseases and COVID-19.- Part 2 Pharmacological Approaches.- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits.- Design and Applications of Genetically-Encoded Voltage-Dependent Calcium Channel Inhibitors.- Part 3 Disease insight from channelopathies: consequences for pharmacology and therapeutic strategies.- CACNA1C-Related Channelopathies.- CACNA1D-Related Channelopathies: From Hypertension to Autism.- CACNA1A-Related Channelopathies: Clinical Manifestations and Treatment Options.- CaV3.2 (CACNA1H) in Primary Aldosteronism,- CaV3.3 Channelopathies.- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits.