TRIM/RBCC Proteins

Häftad, Engelska, 2016

2 179 kr

Beställningsvara. Skickas inom 10-15 vardagar

Fri frakt för medlemmar vid köp för minst 249 kr.

In the first part of this book, we attempt to offer an overview of state-of-the-art basic findings on the tripartite motif (TRIM, also known as RBCC) family members and to deal in the second part with their relevant and growing physiological and pathological roles.

Produktinformation

Utgivningsdatum2016-10-22
Mått178 x 254 x 10 mm
Vikt329 g
FormatHäftad
SpråkEngelska
SerieAdvances in Experimental Medicine and Biology
Antal sidor145
FörlagSpringer-Verlag New York Inc.
ISBN9781493946600

Tillhör följande kategorier

Medicin: allmänt inom Medicin
Biologi inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik
Medicinsk utrustning och medicinska tekniker inom Medicin

Germana Meroni is a graduate of the University of Milan, Italy. She was a post‑graduate fellow at the Department of Biotechnology of the San Raffaele Hospital in Milan, Italy, and then post‑doctoral fellow at the Department of Human and Molecular Genetics of Baylor College of Medicine, Houston, TX (USA). She established her research group at the Telethon Institute of Genetics and Medicine (TIGEM) in Naples and then moved as leader of the Functional Genomics Laboratory at the Cluster in Biomedicine within AREA Science Park in Trieste, Italy. Her main research interest is the genetics and biochemistry of the Tripartite Motif family in health and disease.

Genomics and Evolution of the TRIM Gene Family.- The TRIpartite Motif: Structure and Function.- TRIM Proteins as RING Finger E3 Ubiquitin Ligases.- PML Nuclear Bodies and Other TRIM-Defined Subcellular Compartments.- TRIM Involvement in Transcriptional Regulation.- TRIM Proteins in Cancer.- TRIM Proteins and the Innate Immune Response to Viruses.- The Microtubule-Associated C-I Subfamily of Trim Proteins and the Regulation of Polarized Cell Responses.- MuRFs: Specialized Members of the TRIM/RBCC Family with Roles in the Regulation of the Trophic State of Muscle and Its Metabolism.- TRIM Proteins in Development.