The Proteasomal System in Aging and Disease

• Structure of the ProteasomeTobias Jung and Tilman GruneStructure and Function of the Ubiquitin-Proteasome System: Modulation of ComponentsNiki Chondrogianni and Efstathios S. GonosImmunoproteasomes: Structure, Function, and Antigen Presentation Deborah A. Ferrington and Dale S. GregersonInteractions of the Proteasomal System with Chaperones – Protein Triage and Protein Quality Control Marc Kästle and Tilman GruneProteasome InhibitorsBoris Cvek Degradation of Damaged Proteins - The Main Function of the 20S ProteasomeAndrew. M. Pickering and Kelvin. J. A. Davies Changes of the Proteasomal System During the Aging Process Martin A. Baraibar and Bertrand Friguet Proteasome and Cancer Betul CatalgolThe Ubiquitin Proteasome System and Cardiovascular Disease.Saul R. Powell, Joerg Herrmann, Amir Lerman, Cam Patterson, Xuejun WangRole of the Ubiquitin-Proteasome in Protein Quality Control and Signaling: Implication in the Pathogenesis of Eye DiseasesFu Shang and Allen TaylorProteasome and Neurodegeneratıve Dıseases Betul Catalgol and Tilman Grune

Praise for the series:"Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal