Stroke Genetics

• Preface ; 1. An introduction to stroke ; 2. Genetic principles and techniques ; 3. Genetic epidemiology of stroke ; 4. Genetics of conventional stroke risk factors ; 5. Animal models of stroke: implications for genetic studies of human stroke ; 6. Monogenic causes of ischaemic stroke ; 7. Polygenic ischaemic stroke including new genetic and statistical approaches ; 8. Investigating the genetics of polygenic ischaemic stroke using intermediate phenotypes ; 9. Genetics of intracerebral haemorrhage ; 10. Genetics of subarachnoid haemorrhage and intracranial aneurysms ; 11. Familial cerebral arteriovenous malformations ; 12. The genetics of paediatric stroke ; 13. Investigating a patient with stroke for genetic causes ; 14. Useful web sites for stroke genetics

The book is an essential purchase for physicians and neurologists with an interest in stroke, it covers areas of research not covered in detail by standard texts . . . Although intended for the 'stroke' clinician and the basic scientist entering the field, it is potentially of interest to a much wider audience. I would encourage neurology trainees to read the clinical chapters covering monogenic causes of stroke, intracerebral haemorrhage, aneurysm and arteriovenous malformation, and neurosurgery trainees to read that on the genetics of aneurysm. Medical students and housemen would profit from reading the editor's introductory and final chapters, and if all that is remembered is the table of relative risks for stroke and the importance of taking a systematic family history, two very helpful lessons will have been learnt. Neurology and medical school libraries should certainly obtain a copy.