Screening and Risk Reduction Strategies for Breast Cancer

Masakazu Toi, Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

• 1. Introduction of the whole issue.- 2. Breast cancer epidemiology: incidence, risks and subtype.- 3. Personalized genetic breast cancer risk estimation with polygenic risk scores.- 4. Mathematical model forassessing breast cancer risk.- 5. Cost-effectiveness Analysis of multigene testing.- 6. Hereditary breast cancer: Its biology, subtype and clinical phenotype.- 7. Surgical risk reduction of breast cancer.- 8. Medical risk reduction of breast cancer.- 9. Screening for breast cancer with mammography.- 10. Breast cancer screening: Weighing the benefits and harms.- 11. Breast cancer screening according to individual risk.- 12. MRI: Detection of noninvasive diseases.- 13. Significance of MRI for women having dense breasts .- 14. Ultrasound: screening of breast cancer.- 15. Detection of breast cancer by PET.- 16. Radiowave mammography.- 17. Photoacoustic imaging of breast cancer.

“This text provides a unique angle on exploring the harms of screening for breast cancer with an international perspective that incorporates multimodalities. … The book’s target audience is therefore very diverse and it would act as a great reference to anyone with an interest in the breast cancer field.” (Joleen Kirsty Eden, RAD Magazine, February, 2025)