Saving Lives, Buying Time

For more than 50 years, low-cost antimalarial drugs silently saved millionsof lives and cured billions of debilitating infections. Today, however, thesedrugs no longer work against the deadliest form of malaria that existsthroughout the world. Malaria deaths in sub-Saharan Africa—currently justover one million per year—are rising because of increased resistance to theold, inexpensive drugs. Although effective new drugs called "artemisinins"are available, they are unaffordable for the majority of the affected population,even at a cost of one dollar per course.Saving Lives, Buying Time: Economics of Malaria Drugs in an Age ofResistance examines the history of malaria treatments, provides an overviewof the current drug crisis, and offers recommendations on maximizingaccess to and effectiveness of antimalarial drugs. The book finds that most peoplein endemic countries will not have access to currently effective combinationtreatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify. Table of ContentsFront MatterExecutive SummaryPart 1: A Response to the Current Crisis1 Malaria Today2 The Cost and Cost-Effectiveness of Antimalarial Drugs3 The Case for a Global Subsidy of Antimalarial Drugs4 An International System for Procuring Anitmalarial DrugsPart 2: Malaria Basics5 A Brief History of Malaria6 The Parasite, the Mosquito, and the Disease7 The Human and Economic Burden of Malaria8 Malaria Control9 Antimalarial Drugs and Drug ResistancePart 3: Advancing Toward Better Malaria Control10 Research and Development for New Antimalarial Drugs11 Maximizing the Effective Use of Antimalarial DrugsAcronyms and AbbreviationsGlossaryIndex