Role of Apoptosis in Development, Tissue Homeostasis and Malignancy

Death from inside out

Häftad, Engelska, 2012

Av R.M. Dexter, A.H. Wyllie, M.C. Raff, R. M. Dexter, A. H. Wyllie, M. C. Raff

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Moreover, because a distinct set of biological events is involved in this death, these events themselves become reason able targets for new pharmacological agents in the treatment of cancer. Michael Dexter June 1994 Martin Raff Andrew Wyllie x 1 Death from inside out: an overVIew ANDREW H.

Produktinformation

Utgivningsdatum2012-11-05
Mått210 x 297 x 7 mm
Vikt324 g
FormatHäftad
SpråkEngelska
Antal sidor101
FörlagSpringer
ISBN9789401042451

Tillhör följande kategorier

1 Death from inside out: an overview.- Death in Development.- 2 The ins and outs of programmed cell death during C. elegans development.- 3 Programmed cell death in Drosophila.- 4 Block of neuronal apoptosis by a sustained increase of steady-state free Ca2+ concentration.- 5 Apoptosis in the haemopoietic system.- 6 Programmed cell death and the control of cell survival.- Regulation of Death in Cancer Cells.- 7 Integrated control of cell proliferation and cell death by the c-myc oncogene.- 8 The role of the p53 protein in the apoptotic response.- Signals, Modulators and Effectors.- 9 Apoptosis regulated by a death factor and its receptor: Fas ligand and Fas.- 10 Insights from transgenic mice regarding the role of bcl-2 in normal and neoplastic lymphoid cells.- 11 Molecular mechanisms for B lymphocyte selection: induction and regulation of antigen-receptor-mediated apoptosis of mature B cells in normal mice and their defect in autoimmunity-prone mice.- 12 Fas-based d10S-mediated cytotoxicity requires macromolecular synthesis for effector cell activation but not for target cell death.- Clinical Applications.- 13 Life, death and genomic change in perturbed cell cycles.- 14 Apoptosis and cancer chemotherapy.- 15 Granulocyte apoptosis and the control of inflammation.