Risk Assessment and Management in Cancer Genetics

Häftad, Engelska, 2005

Av Fiona Lalloo, Bronwyn Kerr, J. M Friedman, D Gareth R. Evans, UK) Lalloo, Fiona (Consultant Clinical Geneticist, Academic Unit of Medical Genetics and Regional Genetics Service, St Mary's Hospital, Manchester, UK) Kerr, Bronwyn (Consultant Clinical Geneticist, Academic Unit of Medical Genetics and Regional Genetics Service, St Mary's Hospital, Manchester, Canada) Friedman, J. M (Department of Medical Genetics, University of British Columbia,Vancouver, UK) Evans, D Gareth R. (Professor in Medical Genetics, Academic Unit of Medical Genetics and Regional Genetics Service, St Mary's Hospital, Manchester

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The need to expand expertise in cancer genetics beyond highly specialized genetics clinics is increasingly being recognized. In response, this practical book provides oncologists, specialist nurses, genetic counsellors, family doctors, and geneticists with comprehensive and easy-to-use guidelines on risk assessment and appropriate management.The book focuses on common familial cancers such as breast, colorectal, ovary, prostate and melanoma, and separate chapters cover cancer predisposing syndromes such as neurofibromatosis, familial adenomatous polyposis and their management.

Produktinformation

Utgivningsdatum2005-09-29
Mått168 x 240 x 16 mm
Vikt495 g
FormatHäftad
SpråkEngelska
Antal sidor288
FörlagOUP OXFORD
ISBN9780198529606

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Professor Evans is secretary of the UK Cancer Genetics Group. He was chairman of the UK National Institute of Clinical Excellence guidelines on familial breast cancer, Chairman of the International Collaborative Group on Familial Breast and Ovarian Cancer and on the Editorial Board of Familial Cancer.Professor Friedman is Associate Editor of the journals Genetics in Medicine and Birth Defects Research: Clinical and Molecular Teratology, and a member of the editorial board of Clinical Genetics

INTRODUCTION ; 1. How to evaluate a family history ; 2. Guidelines for referral in Europe ; 3. Guidelines for genetic counselling, testing and referral in North America ; 4. Principles and applications of gene testing for common cancers ; RISK ASSESSMENT OF COMMON MALIGNANCIES ; 5. Risk estimation in breast cancer ; 6. Risk estimation in colorectal cancer ; 7. Risk estimation in ovarian cancer ; 8a Management of familial breast and ovarian cancer in Europe ; 8b Management of familial breast and ovarian cancer in North America ; 9. Management of familial adenomatous polyposis and other inherited polyposis syndromes ; 10. Management of hereditary non-polyposis colorectal cancer ; 11. Management and risk assessment of less common familial cancers ; INHERITED CANCER SYNDROMES ; 12. The neurofibromatoses ; 13. von Hippel-Lindau disease ; 14. Multiple endocrine neoplasias ; 15. Gorlin Syndrome ; 16. The Li-Frameni Syndrome ; 17. Other tumour predisposing syndromes ; 18. The ethical and insurance issues of cancer genetics

One of the commonest questions to a Clinical Genetics department is 'what do I do for this patient with a family history of cancer?' While most departments have guidelines for referral, these are intended to be for quick, easy-view reference. For those many clinicians who would like a little more detail, Lalloo and colleagues have produced this practical text with a worldwide list of contributors...it is easy to find the information you need in this book. Read it from cover to cover if it is valuable to your training or practice (or if you just like the subject) and you will have a comprehensive knowledge of what cancer genetics is about; keep it for reference, dipping into the particular bit you need from time to time, and your clinical genetics colleagues will be very impressed with your knowledge.