Regulatory T Cells in Health and Disease

Adrian Liston is Professor in Autoimmune Genetics at the University of Leuven and the VIB, Belgium. His PhD research was on T cell tolerance and diabetes with Professor Chris Goodnow at the Australian National University, followed by post-doctoral research on regulatory T cell biology with Professor Sasha Rudensky at the University of Washington. The Liston laboratory is supported by an ERC Start Grant, a JDRF Career Development Award, a VIB Investigators Award and grants from the FWO and KUL. Adrian Liston has published more than 70 papers, with over 3000 citations, including key publications on the function of Aire in thymic tolerance, defective tolerance in the NOD mouse, the contribution of immunodeficiency to autoimmunity, microRNA function in regulatory T cells, the discovery of the follicular regulatory T cell, the role of microRNA in the thymic epithelium and the homeostatic control over regulatory T cells.

• Transcriptional and Epigenetic Regulation of Regulatory T Cell DevelopmentYohko Kitagawa, James Badger Wing and Shimon SakaguchiMicroenvironment Matters: Unique Conditions within Gut Draining Lymph Nodes Favor Efficient de Novo Induction of Regulatory T CellsMaria Pasztoi, Joern Pezoldt and Jochen HuehnThe Roles of the Nf-Κb Pathway in Regulatory T Cell Development and FunctionThomas S. Fulford, Darcy Ellis and Steve GerondakisThe Molecular Control of Regulatory T Cell InductionAnnemarie van Nieuwenhuijze and Adrian ListonThe Special Relationship in the Development and Function of T Helper 17 and Regulatory T CellsMatthias Lochner, Zuobai Wang and Tim SparwasserMechanisms of Surveillance of Dendritic Cells by Regulatory T LymphocytesMaxime Dhainaut and Muriel MoserDevelopment and Function of Effector Regulatory T cellsPeggy P. Teh, Ajithkumar Vasanthakumar and Axel KalliesTreg Cell Differentiation: from Thymus to Peripheral TissueDavid M. Richards, Michael Delacher, Yael Goldfarb, Danny Kägebein,  Ann-Cathrin Hofer, Jakub Abramson  and Markus FeuererRegulatory T Cells in ArthritisNoriko Komatsu and Hiroshi TakayanagiThe Immune Fulcrum: Regulatory T Cells Tip the Balance Between Pro- and  Anti-Inflammatory Outcomes Upon Infection Laura E. Richert-Spuhler and Jennifer M. LundRegulatory T Cells in Autoimmune Diabetes: Mechanisms of Action and Translational PotentialVitalijs Ovcinnikovs and Lucy S.K. Walker