Recent Advances in the Science of Cannabis

Inbunden, Engelska, 2021

AvRobert M. Strongin,Jiries Meehan-Atrash,Monica Vialpando

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Recent Advances in the Science of Cannabis describes progress in a variety of significant areas of cannabis science. This unique book covers topics in cultivation and secondary metabolites, aroma and chemotypes, cannabinoid structures, physiology and pharmacology, as well as the development of unique topical products. State-of-the-art analytical methods and instrumentation are covered, including current developments in mass spectrometry and chromatography, as well as microbial testing. Given the popularity of smoking and vaporizing cannabis, the chemistry of vaping cannabinoid and terpene concentrates is also presented, along with emerging regulatory issues.Key Features:A guide to emerging modern cannabis technology in a dynamic regulatory climate and appealing to both novices and specialists. Building upon pioneering studies of terpene and cannabinoid chemistry, this distinctive volume describes current best practices, technological breakthroughs and historical context.Written by researchers in industry and academia, a greater understanding of the risks of exposure to emissions from vaping or dabbing cannabis concentrates is provided here.A selection of the book content reviewing Thermal Degradation of Cannabinoids and Cannabis Terpenes has been included in “Hot 2021” RSC Advances.

Produktinformation

Utgivningsdatum2021-11-22
Mått156 x 234 x 22 mm
Vikt600 g
FormatInbunden
SpråkEngelska
Antal sidor280
FörlagTaylor & Francis Ltd
ISBN9780367224424

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Robert M. Strongin is a Professor of Organic Chemistry at Portland State University.He has studied the chemistry of vaping since 2013. He has been interested in determininghow flavorings, including terpenes and other vape constituents, react anddegrade when heated and aerosolized. In 2017 he began to investigate cannabis vapingand published the first peer-reviewed reports on the specific byproducts formedwhen dabbing terpenes, and, more recently, on the reactions and products that formupon vaping and dabbing concentrated cannabis oil mixtures. Dr. Strongin runs aninternationally recognized research program, is a founder of two biotech startupcompanies, and is known for his contributions to STEM education. In addition totobacco control and cannabis science, he is an expert in the field of biosensors andtargeted molecular probes for imaging cancer tissue.Monica Vialpando is a pharmaceutically trained product development scientist,specializing in the formulation of poorly water-soluble drugs. As founder and CEOof Via Innovations, a bespoke product development company, she integrates thisbackground with plant-based medicines to create fit-for-purpose designed products.In addition to her entrepreneurial endeavors, she is active in education and thoughtleadership and often focuses on cannabis-based strategies to support women’s health,and is a scientific advisor to multiple organizations. With a passion for diversity andglobal connection, Dr. Vialpando’s reach extends beyond typical barriers to collaboratewith international experts and companies. She also leverages this throughouther company to design their differentiated products through the integration of plantbasedmedicines, science, technology, and art.Jiries Meehan-Atrash graduated from the State University of New York at NewPaltz with a Bachelor of Science in Chemistry in 2014 and in 2021 earned his PhD inChemistry from Portland State University after studying e-cigarette aerosol chemistryand analytical methods under the mentorship of Dr. Robert M. Strongin. Jiries iscurrently a postdoctoral fellow at the University of Rochester Medical Center in thelaboratory of Dr. Irfan Rahman.

ContentsPreface......................................................................................................................viiEditors........................................................................................................................ixContributors...............................................................................................................xiChapter 1 Cultivation Stress Techniques and the Production of SecondaryMetabolites in Cannabis sativa.............................................................1Callie SeamanChapter 2 Aroma in Cannabis: A Foundation for Chemotype Classification..... 31John S. Abrams, William J. T. Ellyson, Victor J. Gomez, andJean L. TalleyrandChapter 3 Cannabinoid Chemistry of Cannabis.................................................. 49David Dawson and Markus RoggenChapter 4 Use of Mass Spectrometry for the Analysis of Cannabissativa spp......................................................................................... 79Allegra Leghissa and Zacariah L. HildenbrandChapter 5 New Trends in the Analysis of Cannabis-Based Products................ 111Laura Mercolini, Roberto Mandrioli and Michele ProttiChapter 6 Cannabis Microbial Testing: Methodologies and Considerations..... 131Kyle BoyarChapter 7 Cannabis Extract Formulations and Devices.................................... 161Brad Douglass and Robert M. StronginChapter 8 Transdermal Delivery........................................................................ 193Carolyn Burek, Jessica Painter, and Monica VialpandoChapter 9 Thermal Degradation of Cannabinoids and Cannabis Terpenes:A Review........................................................................................... 215Jiries Meehan-Atrash and Robert M. StronginChapter 10 Cannabis Pharmacokinetics and Pharmacodynamics...................... 235Ted W. SimonIndex....................................................................................................................... 267