Principles of Bioinspired and Biomimetic Regenerative Medicine

Farnaz Ghorbani: Farnaz Ghorbani, PhD in Biomaterials, is a Research Fellow at Bristol Medical School, University of Bristol (UK), specializing in biomaterials and translational tissue engineering. She has received several prestigious awards and has led multiple multidisciplinary research projects as a Principal Investigator at Friedrich-Alexander University Erlangen-Nuremberg (Germany), University College London (UK), and Fudan University (China). She co-founded a company specializing in biomaterials and 3D printing (Tehran, Iran), underscoring her commitment to translating research into real-world applications. Her expertise lies in the design and development of bioinspired structures and materials, drawing inspiration from nature to engineer advanced biomaterials for regenerative medicine. Her research encompasses protein-mediated surface functionalization, aiming to enhance cell-material interactions and direct tissue regeneration. With a strong focus on translational strategies for osteochondral defect repair, she integrates surface modification techniques, bio-inspired scaffolds, and biomaterials-driven approaches to bridge the gap between fundamental research and clinical applications.Behafarid Ghalandari: Behafarid Ghalandari, PhD in Biophysics, is a Research Fellow at the Division of Surgery and Interventional Science at University College London, specializing in biophysics and computational biomaterials research. His work has earned several prestigious awards, and he has led multiple interdisciplinary research projects as a principal investigator. He explores protein-based nanostructures and peptide-based materials using in silico and experimental methods, with applications in biomaterials science and biomedical engineering. Additionally, he investigates how proteins and peptides modify material surfaces to enhance biomaterial properties. His research also focuses on polymer- and nanoparticle-protein interactions, studied through spectroscopic and computational techniques. Leveraging his multidisciplinary expertise, he advances computational modelling and materials science, contributing to the development of novel biomaterials for medical and nanotechnology applications.Chaozong Liu: Chaozong Liu is a Professor of Orthopaedic Bioengineering at UCL Institute of Orthopaedics & Musculoskeletal Science, Division of Surgery & Interventional Science, in associate with the Royal National Orthopaedic Hospital Stanmore. He is the MSc in Musculoskeletal Science Course Tutor, Group Leader of UCL Orthopaedic Bioengineering Group and the Director of Centre for Bioengineering and Surgical Technology the Division of Surgery and Interventional Science, University College London. His current research is directed toward biomedical devices processing for enhancing the early diagnosis and treatment of musculoskeletal disorders. Specifically, his research interest includes (1) design and development of scaffolds for musculoskeletal tissue engineering and regenerative medicine. (2) Customized medical devices for intervention of musculoskeletal disorders. (3) biomedical device surface processing for regulate protein adsorption and cells attachment. (4) biomaterials and additive manufacturing innovation for orthopaedic medical devices.

• Part 1: Introduction.- CH1. The concept and history of bioinspired and biomimetic regenerative medicine.- Part 2. Bioinspired and biomimetic materials for regenerative medicine.- CH2. Bioinspired polymers for regenerative medicine.- CH3. Bioinspired and biomimetic hydrogels for regenerative medicine.- CH4. Biomimetic ceramics for regenerative medicine.- CH5. Lipid-based systems for regenerative medicine.- CH6. Glycan-based systems for regenerative medicine.- CH7. Peptide-based systems for regenerative medicine.- CH8. Nucleic acid-based systems for regenerative medicine.- Part 3: Bioinspired design for regenerative medicine.- CH9. Nature-inspired architecture for regenerative medicine.- CH10. Smart bio-inspired structures: Organ-on-chip.- CH11. Bioinspired self-assembled nanotechnology for regenerative medicine.- CH12. Bioinspired surface technology for regenerative medicine.- CH13. Biochemical and biophysical design of materials for regenerative medicine.- Part 4: Application of bioinspired and biomimetic materials/architecture.- CH14. Bioinspired and biomimetic materials/architecture in bone regeneration.- CH15. Bioinspired and biomimetic materials/architecture in cartilage regeneration.- CH16. Bioinspired and biomimetic materials/architecture in tendon and ligament regeneration.- CH17. Intervertebral disc regeneration using biomimetic materials and bio-inspired architecture.- CH18. Bioinspired and biomimetic materials/architecture in muscle regeneration.- CH19. Bioinspired and biomimetic materials/architecture in cardiovascular regeneration.- CH20. Bioinspired and biomimetic materials/architecture in skin regeneration.- Part 5: Method of characterization of bioinspired and biomimetic materials/ architecture.- CH21. Wet-lab techniques for characterizing bioinspired materials and structures for regenerative medicine.- CH22. Dry-lab computational approaches for simulating bioinspired materials/structures for regenerative medicine.- CH23. Advancement of synthetic biology strategies for bioinspired regenerative medicine.