Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

Häftad, Engelska, 2018

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The authoritative reference to bone diseases and disorders of mineral metabolism, revised and updatedNow in its ninth edition, The Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism offers an updated and comprehensive guide to bone and mineral health. Since it was first published 30 years ago, the Primer has become the leading reference on the topic. With contributions from noted experts, the text explores basic biological factors of healthy development and disease states and makes the information accessible for clinical interventions. The ninth edition provides concise coverage of the widest possible spectrum of metabolic bone diseases and disorders of mineral metabolism.The new edition of this invaluable reference expands coverage and includes the most recent developments in the field that help to strengthen its usefulness and ensure that the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism maintains its place as the pre-eminent reference on bone and mineral health. This vital resource: Provides the most accurate, up-to-date evidence-based information on basic and clinical bone scienceIncludes more than 10 new chapters and contributions from 300 authors from wide-ranging international research centersCaptures the very cutting edge of research covering mineral homeostasis, osteoporosis and other metabolic bone diseases, skeletal measurement technologies, and geneticsPresents a new companion website with useful supplementary materials at www.asbmrprimer.comWritten for advanced students, clinicians, and researchers working in the field of bone health and disease, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism is the definitive, one-stop reference for anyone working in the field of bone health and disease.

Produktinformation

Utgivningsdatum2018-11-16
Mått216 x 279 x 48 mm
Vikt2 835 g
FormatHäftad
SpråkEngelska
Antal sidor1 136
Upplaga9
FörlagJohn Wiley and Sons Ltd
MedarbetareBilezikian,JohnP.
ISBN9781119266563

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Muskuloskeletala sjukdomar inom Medicin
Fysiologi inom Medicin

John P. Bilezikian is the Dorothy L. and Daniel H. Silberberg Professor of Medicine and Professor of Pharmacology at the College of Physicians & Surgeons, Columbia University. He is Chief Emeritus of the Division of Endocrinology and Vice-chair of the Department of Medicine for International Research and Education. He is also Director Emeritus of the Metabolic Bone Diseases Program at Columbia University Medical Center.

Contributors xiPreface to the Ninth Edition of the Primer:John P. Bilezikian xxivAbout ASBMR xxvPresident’s Preface Michael J. Econs xxviAbout the Companion Website xxviiSection I Molecular and Cellular Determinants of Bone Structure and Function 1Section Editor Karen Lyons1 Early Skeletal Morphogenesis in Embryonic Development 3Yingzi Yang2 Endochondral Ossification 12Courtney M. Karner and Matthew J. Hilton3 Local and Circulating Osteoprogenitor Cells and Lineages 20Naomi Dirckx and Christa Maes4 Osteoblasts Function, Development, and Regulation 31Elizabeth W. Bradley, Jennifer J. Westendorf, Andre J. van Wijnen, and Amel Dudakovic5 Osteocytes 38Lynda F. Bonewald6 Osteoclast Biology and Bone Resorption 46Hiroshi Takayanagi7 Signal Transduction Cascades Controlling Osteoblast Differentiation 54David J.J. de Gorter, Gonzalo Sánchez‐Duffhues, and Peter ten Dijke8 The TGF‐β Superfamily in Bone Formation and Maintenance 60Ce Shi and Yuji Mishina9 Recent Developments in Understanding the Role of Wnt Signaling in Skeletal Development and Disease 68Zhendong A. Zhong, Nicole J. Ethen, and Bart O. Williams10 Mechanotransduction in Bone Formation and Maintenance 75Whitney A. Bullock, Lilian I. Plotkin, Alexander G. Robling, and Fredrick M. Pavalko11 The Composition of Bone 84Adele L. Boskey and Pamela G. Robey12 Assessment of Bone Mass, Structure, and Quality in Rodents 93Jeffry S. Nyman and Deepak Vashishth13 Skeletal Healing Cellular and Molecular Determinants 101Alayna E. Loiselle and Michael J. Zuscik14 Biomechanics of Fracture Healing 108Elise F. Morgan, Amira I. Hussein, and Thomas A. EinhornSection II Skeletal Physiology 115Section Editor Ego Seeman15 Human Fetal and Neonatal Bone Development 117Tao Yang, Monica Grover, Kyu Sang Joeng, and Brendan Lee16 Skeletal Growth a Major Determinant of Bone’s Structural Diversity in Women and Men 123Ego Seeman17 Racial Differences in the Acquisition and Age‐related Loss of Bone Strength 131Shane A. Norris, Marcella D. Walker, Kate Ward, Lisa K. Micklesfield, and John M. Pettifor18 Calcium, Vitamin D, and Other Nutrients During Growth 135Tania Winzenberg and Graeme Jones19 Mechanical Loading and the Developing Skeleton 141Mark R. Forwood20 Pregnancy and Lactation 147Christopher S. Kovacs and Henry M. Kronenberg21 Menopause and Age‐related Bone Loss 155Carlos M. Isales and Ego SeemanSection III Mineral Homeostasis 163Section Editors David Goltzman and Harald Jüppner22 Regulation of Calcium Homeostasis 165Line Vautour and David Goltzman23 Magnesium Homeostasis 173Aliya Aziz Khan, Asiya Sbayi, and Karl Peter Schlingmann24 Fetal Calcium Metabolism 179Christopher S. Kovacs25 FGF23 and the Regulation of Phosphorus Metabolism 187Kenneth E. White and Michael J. Econs26 Gonadal Steroids 194Stavros C. Manolagas and Maria Schuller Almeida27 Parathyroid Hormone 205Thomas J. Gardella, Robert A. Nissenson, and Harald Jüppner28 Parathyroid Hormone‐Related Protein 212John J. Wysolmerski and T. John Martin29 Calcium‐Sensing Receptor 221Geoffrey N. Hendy30 Vitamin D Production, Metabolism, Action, and Clinical Requirements 230Daniel D. Bikle, John S. Adams, and Sylvia ChristakosSection IV Investigation of Metabolic Bone Diseases 241Section Editors Douglas C. Bauer and Klaus Engelke31 Techniques of Bone Mass Measurement in Children with Risk Factors for Osteoporosis 243Nicola J. Crabtree and Leanne M. Ward32 Standard Techniques of Bone Mass Measurement in Adults 252E. Michael Lewiecki, Paul D. Miller, and Nelson B. Watts33 Advanced Techniques of Bone Mass Measurements and Strength in Adults 260Kyle K. Nishiyama, Enrico Dall’Ara, and Klaus Engelke34 Magnetic Resonance Imaging of Bone 272Sharmila Majumdar35 Trabecular Bone Score 277Barbara C. Silva and William D. Leslie36 Reference Point Indentation 287Adolfo Diez‐Perez and Joshua N. Farr37 Biochemical Markers of Bone Turnover in Osteoporosis 293Pawel Szulc, Douglas C. Bauer, and Richard Eastell38 Scintigraphy and PET in Metabolic Bone Disease 302Lorenzo Nardo, Paola A. Erba, and Benjamin L. Franc39 Bone Histomorphometry in Clinical Practice 310Robert R. Recker and Carolina Aguiar Moreira40 Diagnosis and Classification of Vertebral Fracture 319James F. Griffith and Harry K. Genant41 FRAX Assessment of Fracture Risk 331John A. Kanis, Eugene V. McCloskey, Nicholas C. Harvey, and William D. LeslieSection V Genetics of Bone 341Section Editor Rajesh V. Thakker42 Introduction to Genetics 343Paul J. Newey, Michael P. Whyte, and Rajesh V. Thakker43 Animal Models Genetic Manipulation 351Karen Lyons44 Animal Models Allelic Determinants for Bone Mineral Density 359J. H. Duncan Bassett, Graham R. Williams, and Robert D. Blank45 Transcriptional Profiling for Genetic Assessment 367Aimy Sebastian and Gabriela G. Loots46 Approaches to Genetic Testing 373Christina Jacobsen, Yiping Shen, and Ingrid A. Holm47 Human Genome‐Wide Association Studies 378Douglas P. Kiel, Emma L. Duncan, and Fernando Rivadeneira48 Translational Genetics of Osteoporosis From Population Association to Individualized Assessment 385Bich Tran, Jacqueline R. Center, and Tuan V. NguyenSection VI Osteoporosis 393Section Editors Paul D. Miller, Socrates E. Papapoulos, and Michael R. McClung49 Osteoporosis an Overview 395Michael R. McClung, Paul D. Miller, and Socrates E. Papapoulos50 The Epidemiology of Osteoporotic Fractures 398Nicholas C. Harvey, Elizabeth M. Curtis, Elaine M. Dennison, and Cyrus Cooper51 Fracture Liaison Service 405Piet Geusens, John A. Eisman, Andrea Singer, and Joop van den Bergh52 Sex Steroids and the Pathogenesis of Osteoporosis 412Matthew T. Drake and Sundeep Khosla53 Juvenile Osteoporosis 419Francis H. Glorieux and Craig Munns54 Transplantation Osteoporosis 424Peter R. Ebeling55 Premenopausal Osteoporosis 436Adi Cohen and Elizabeth Shane56 Osteoporosis in Men 443Eric S. Orwoll and Robert A. Adler57 Bone Stress Injuries 450Stuart J. Warden and David B. Burr58 Inflammation‐Induced Bone Loss in the Rheumatic Diseases 459 Ellen M. Gravallese and Steven R. Goldring59 Glucocorticoid‐Induced Osteoporosis 467Kenneth Saag and Robert A. Adler60 Human Immunodeficiency Virus and Bone 474Michael T. Yin and Todd T. Brown61 Effects on the Skeleton from Medications Used to Treat Nonskeletal Disorders 482Nelson B. Watts62 Diabetes and Fracture Risk 487Serge Ferrari, Nicola Napoli, and Ann Schwartz63 Obesity and Skeletal Health 492Juliet Compston64 Sarcopenia and Osteoporosis 498Gustavo Duque and Neil Binkley65 Management of Osteoporosis in Patients with Chronic Kidney Disease 505Paul D. Miller66 Other Secondary Causes of Osteoporosis 510Neveen A. T. Hamdy and Natasha M. Appelman‐Dijkstra67 Exercise for Osteoporotic Fracture Prevention and Management 517Robin M. Daly and Lora Giangregorio68 Prevention of Falls 526Heike A. Bischoff‐Ferrari69 Nutritional Support for Osteoporosis 534Connie M. Weaver, Bess Dawson‐Hughes, Rene Rizzoli, and Robert P. Heaney70 Estrogens, Selective Estrogen Receptor Modulators, and Tissue‐Selective Estrogen Complex 541Tobias J. de Villiers71 Bisphosphonates for Postmenopausal Osteoporosis 545Andrea Giusti and Socrates E. Papapoulos72 Denosumab 553Aline Granja Costa, E. Michael Lewiecki, and John P. Bilezikian73 Parathyroid Hormone and Abaloparatide Treatment for Osteoporosis 559Felicia Cosman and Susan L. Greenspan74 Combination Anabolic and Antiresorptive Therapy for Osteoporosis 567Joy N. Tsai and Benjamin Z. Leder75 Strontium Ranelate and Calcitonin 573Leonardo Bandeira and E. Michael Lewiecki76 Adverse Effects of Drugs for Osteoporosis 579Bo Abrahamsen and Daniel Prieto‐Alhambra77 Orthopedic Principles of Fracture Management 588Manoj Ramachandran and David G. Little78 Adherence to Osteoporosis Therapies 593Stuart L. Silverman and Deborah T. Gold79 Cost‐Effectiveness of Osteoporosis Treatment 597Anna N.A. Tosteson80 Future Therapies 603Michael R. McClungSection VII Metabolic Bone Diseases 611Section Editors Suzanne M. Jan de Beur and Peter R. Ebeling81 Approach to Parathyroid Disorders 613John P. Bilezikian82 Primary Hyperparathyroidism 619Shonni J. Silverberg, Francisco Bandeira, Jianmin Liu, Claudio Marcocci, and Marcella D. Walker83 Familial States of Primary Hyperparathyroidism 629Andrew Arnold, Sunita K. Agarwal, and Rajesh V. Thakker84 Non‐Parathyroid Hypercalcemia 639Mara J. Horwitz85 Hypocalcemia Definition, Etiology, Pathogenesis, Diagnosis, and Management 646Anne L. Schafer and Dolores M. Shoback86 Hypoparathyroidism 654Tamara Vokes, Mishaela R. Rubin, Karen K. Winer, Michael Mannstadt, Natalie E. Cusano, Harald Jüppner, and John P. Bilezikian87 Pseudohypoparathyroidism 661Agnès Linglart, Michael A. Levine, and Harald Jüppner88 Disorders of Phosphate Homeostasis 674Mary D. Ruppe and Suzanne M. Jan de Beur89 Rickets and Osteomalacia 684Michaël R. Laurent, Nathalie Bravenboer, Natasja M. Van Schoor, Roger Bouillon, John M. Pettifor, and Paul Lips90 Pathophysiology and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder 695Mark R. Hanudel, Sharon M. Moe, and Isidro B. Salusky91 Disorders of Mineral Metabolism in Childhood 705Thomas O. Carpenter and Nina S. Ma92 Paget Disease of Bone 713Julia F. Charles, Ethel S. Siris, and G. David Roodman93 Epidemiology, Diagnosis, Evaluation, and Treatment of Nephrolithiasis 721Murray J. Favus and David A. Bushinsky94 Immobilization and Burns Other Conditions Associated with Osteoporosis 730William A. Bauman, Christopher Cardozo, and Gordon L. KleinSection VIII Cancer and Bone 737Section Editors Theresa Guise and G. David Roodman95 Mechanisms of Osteolytic and Osteoblastic Skeletal Lesions 739G. David Roodman and Theresa Guise96 Clinical and Preclinical Imaging in Osseous Metastatic Disease 743Siyang Leng and Suzanne Lentzsch97 Metastatic Tumors and Bone 752Julie A. Sterling and Rachelle W. Johnson98 Myeloma Bone Disease and Other Hematological Malignancies 760Claire M. Edwards and Rebecca Silbermann99 Osteogenic Osteosarcoma 768Yangjin Bae, Huan‐Chang Zeng, Linchao Lu, Lisa L. Wang, and Brendan Lee100 Skeletal Complications of Breast and Prostate Cancer Therapies 775Catherine Van Poznak and Pamela Taxel101 Bone Cancer and Pain 781Denis Clohisy and Lauren M. MacCormick102 Radiotherapy‐Induced Osteoporosis 788Laura E. Wright103 Skeletal Complications of Childhood Cancer 793Manasa Mantravadi and Linda A. DiMeglio104 Medical Prevention and Treatment of Bone Metastases 799Catherine Handforth, Stella D’Oronzo, and Janet Brown105 Radiotherapy of Skeletal Metastases 809Srinivas Raman, K. Liang Zeng, Oliver Sartor, Edward Chow, and Øyvind S. Bruland106 Concepts and Surgical Treatment of Metastatic Bone Disease 816Kristy Weber and Scott L. KominskySection IX Sclerosing and Dysplastic Bone Diseases 823Section Editor Michael P. Whyte107 Sclerosing Bone Disorders 825Michael P. Whyte108 Fibrous Dysplasia 839Michael T. Collins, Alison M. Boyce, and Mara Riminucci109 The Osteochondrodysplasias 848Fabiana Csukasi and Deborah Krakow110 Ischemic and Infiltrative Disorders of Bone 853Michael P. Whyte111 Tumoral Calcinosis – Dermatomyositis 861Nicholas J. Shaw112 Genetic Disorders of Heterotopic Ossification: Fibrodysplasia Ossificans Progressiva and Progressive OsseousHeteroplasia 865Frederick S. Kaplan, Robert J. Pignolo, Mona Al Mukaddam, and Eileen M. Shore113 Osteogenesis Imperfecta 871Joan C. Marini114 Fibrillinopathies Skeletal Manifestations of Marfan Syndrome and Marfan‐Related Conditions 878Gary S. Gottesman and Michael P. Whyte115 Hypophosphatasia and Other Enzyme Deficiencies Affecting the Skeleton 886Michael P. WhyteSection X Oral and Maxillofacial Biology and Pathology 891Section Editor Laurie McCauley116 Craniofacial Morphogenesis 893Erin Ealba Bumann and Vesa Kaartinen117 Development and Structure of Teeth and Periodontal Teeth 901Petros Papagerakis and Thimios Mitsiadis118 Genetic Craniofacial Disorders Affecting the Dentition 911Yong‐Hee Patricia Chun, Paul H. Krebsbach, and James P. Simmer119 Pathology of the Hard Tissues of the Jaws 918Paul C. Edwards120 Osteonecrosis of the Jaw 927Sotirios Tetradis, Laurie McCauley, and Tara Aghaloo121 Alveolar Bone Homeostasis in Health and Disease 933Chad M. Novince and Keith L. Kirkwood122 Oral Manifestations of Metabolic Bone Diseases 941Erica L. Scheller, Charles Hildebolt, and Roberto Civitelli123 Dental Implants and Osseous Healing in the Oral Cavity 949Takashi Matsuura and Junro YamashitaSection XI Integrative Physiology of the Skeleton 957Section Editors Mone Zaidi and Clifford J. Rosen124 Integrative Physiology of the Skeleton 959Clifford J. Rosen and Mone Zaidi125 The Hematopoietic Niche and Bone 966Stavroula Kousteni, Benjamin J. Frisch, Marta Galan‐Diez, and Laura M. Calvi126 Adipocytes and Bone 974Clarissa S. Craft, Natalie K. Wee, and Erica L. Scheller127 The Vasculature and Bone 983Marie Hélène Lafage‐Proust and Bernard Roche128 Immunobiology and Bone 992Roberto Pacifici and M. Neale Weitzmann129 Cellular Bioenergetics of Bone 1004Wen‐Chih Lee and Fanxin Long130 Endocrine Bioenergetics of Bone 1012Patricia F. Ducy and Gerard Karsenty131 Central Neuronal Control of Bone Remodeling 1020Hiroki Ochi, Paul Baldock, and Shu Takeda132 Peripheral Neuronal Control of Bone Remodeling 1028Katherine J. Motyl and Mary F. Barbe133 The Pituitary–Bone Axis in Health and Disease 1037Mone Zaidi, Tony Yuen, Wahid Abu‐Amer, Peng Liu, Terry F. Davies, Maria I. New, Harry C. Blair, Alberta Zallone, Clifford J. Rosen, and Li Sun134 Neuropsychiatric Disorders and the Skeleton 1047Madhusmita Misra and Anne Klibanski135 Interactions Between Muscle and Bone 1055Marco BrottoIndex 1063