The commonly held impression is that [neglected tropical diseases (NTDs)] are a "global" issue, i.e., a problem "over there." Not so, argue the authors of this book. According to them, NTDs are more prevalent than expected in the American South. They prosper there not only because of climate but also because of poverty. Hence, eradication or mitigation requires policy changes in recognition of their common social determinants, in addition to specific medical and public health efforts. Blackburn and Lively present a passionate call to action that is well researched and clearly argued. Highly recommended. Upper-division undergraduates. Graduate students, faculty, and professionals.