Del 282 - Current Topics in Microbiology and Immunology

Phosphoinositides in Subcellular Targeting and Enzyme Activation

Inbunden, Engelska, 2003

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Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.

Produktinformation

Utgivningsdatum2003-09-15
Mått155 x 235 x 19 mm
Vikt554 g
FormatInbunden
SpråkEngelska
SerieCurrent Topics in Microbiology and Immunology
Antal sidor209
Upplaga2004
FörlagSpringer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN9783540009504

Tillhör följande kategorier

Biokemi inom Naturvetenskap och teknik
Onkologi inom Medicin

List of Contents.- Phosphoinositide Involvement in Phagocytosis and Phagosome Maturation.- Regulation of Endocytosis by Phosphatidylinositol 4,5-Biphosphate and ENTH Proteins.- Membrane Targeting by Pleckstrin Homology Domains.- Protein Targeting to Endosomes and Phagosomes via FYVE and PX Domains.- Regulation of the Actin Cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3.- Roles of PI3K in Neutrophil Function.- Nuclear Phosphoinositides and Their Functions.

From the reviews:"The book consists of seven chapters that focus on the various functions of PtdIns. … summarises recent advances in the burgeoning field of inositol lipids and provides a snapshot of where the field stands in 2003. The field is moving rapidly but this volume will be a useful addition for many researchers who have only recently discovered that their favourite protein is regulated by PtdIns." (Shamshad Cockcroft, nature cell biology, Vol. 6 (6), June, 2004)