Pediatric Epilepsy Surgery Techniques

Controversies and Evidence

Häftad, Engelska, 2024

Av Aria Fallah, George M. Ibrahim, Alexander G. Weil, David Geffen School of Medicine at UCLA) Fallah, Aria (Pediatric and Adult Epilepsy Neurosurgeon, Ronald Reagan UCLA Medical Center and UCLA Mattel Children’s Hospital Associate Professor of Neurosurgery and Pediatrics, Canada) Ibrahim, George M. (Paediatric Neurosurgeon, The Hospital for Sick Children (SickKids); Associate Professor in Biomedical Engineering, Institute of Medical Sciences; Department of Surgery, University of Toronto, Canada) Weil, Alexander G. (Pediatric Neurosurgeon, Sainte-Justine University Hospital; Associate Professor, Department of Surgery and Neuroscience, University of Montreal, George M. Associate in Biomedical Engineering Ibrahim

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Pediatric Epilepsy Surgery Techniques: Controversies and Evidence offers clinicians a roadmap for navigating the complex decision-making process involved in selecting surgical interventions for children with drug-resistant epilepsy. Over the last decade, the landscape of pediatric epilepsy surgery has undergone substantial transformation, marked by the introduction of several emerging technologies that are now supported by an expanding body of evidence, yet leading to a wide range of treatment practices. This book addresses several decision-making dichotomies in pediatric epilepsy surgery, both in terms of established and novel surgical modalities and techniques. The book explores long-standing debated topics, such as the relative benefits of disconnective compared to resective strategies, the utility of surgical adjuncts like intra-operative electrocorticography, as well as rationales for different surgical approaches, namely selective amygdalo-hippocampectomy versus anteromesial temporal lobectomy. Further, it addresses dichotomies between traditional approaches and contemporary modalities, such as microsurgical resection versus laser interstitial thermal therapy. Chapters also offer comparisons of modern technologies, such as different neuromodulation strategies, including vagus nerve stimulation, deep brain stimulation, and responsive neurostimulation.

This book provides readers with the relevant scientific literature and expert commentary to inform evidence-based approaches to surgical care in pediatric drug-resistant epilepsy.

Discusses state-of-the-art technology in the surgical treatment of pediatric drug-resistant epilepsy
Provides an up-to-date overview of current controversies, competing approaches, and their relative evidence, indications, advantages, and disadvantages for pediatric epilepsy surgery
Outlines evidence-based recommendations to guide decision-making in pediatric epilepsy surgery

Produktinformation

Utgivningsdatum2024-11-18
Mått152 x 229 x 23 mm
Vikt630 g
FormatHäftad
SpråkEngelska
Antal sidor396
FörlagElsevier Science
ISBN9780323959810

Tillhör följande kategorier

Pediatrik inom Medicin
Neurologi och klinisk neurofysiologi inom Medicin

Dr. Aria Fallah is a paediatric and adult epilepsy neurosurgeon at the Ronald Reagan UCLA Medical Center and UCLA Mattel Children’s Hospital. He serves as the Director of Epilepsy Surgery and Pediatric Neurosurgery at UCLA. He holds the Alfonsina Q. Davies Chair in Epilepsy Research. Dr. Fallah is an Associate Professor of Neurosurgery and Pediatrics at the David Geffen School of Medicine at UCLA, as well as an Associate Professor in Health Policy & Management at the UCLA Fielding School of Public Health. He is also a member of the Brain Research Institute at UCLA. In addition to his medical qualifications, he has obtained his Executive MBA from the UCLA Anderson School of Management. His clinical practice focuses on the surgical management of children with medically intractable epilepsy.Dr. George Ibrahim is the Abe Bresver Chair in Functional Neurosurgery at the Hospital for Sick Children and Associate Professor in Surgery, Biomedical Engineering and Medical Science at the University of Toronto. He is a Scientist in the Program in Neuroscience and Mental Health at the Hospital for Sick Children Research Institute. He is the Surgical Director of the pediatric DBS program. Dr. Weil is a pediatric and epilepsy neurosurgeon at Sainte-Justine University Hospital and the University of Montreal Hospital Center (CHUM). He serves as an Associate Professor in the Departments of Surgery and Neuroscience at the University of Montreal. Additionally, he is a Surgeon-Scientist in the Brain and Child Development Axis at the CHU Sainte-Justine Research Institute. Dr. Weil is the Director of the University of Montreal Pediatric Neurosurgery Fellowship and the research representative for the University of Montreal Division of Neurosurgery. His clinical practice and expertise focus on the investigation and treatment of drug-resistant epilepsy in both pediatric and adult populations.

Part 1: Evidence in pediatric epilepsy surgery1. Evidence in pediatric epilepsy surgeryChurl-Su Kwon and Varun Ramanan Subramaniam2. Controversies in the timing of pediatric epilepsy surgery—is earlier better?Jarod L. RolandPart 2: Invasive investigation3. Electroencephalographic evaluation of epileptogenicity—traditional versus novel biomarkers to guide surgeryEroshini Swarnalingam and Julia Jacobs4. Invasive monitoring: stereoelectroencephalography (sEEG) versus subdural electrode (SDE) versus hybrid evaluationTaylor J. Abel, Luis Fernandez and Joseph GarciaPart 3: Resective or ablative surgery5. Intraoperative adjuncts to optimize the surgical treatment of drug-resistant epilepsy—do new tools improve outcome?Trang Tran, Frederic Leblond and Roy W.R. Dudley6. Medial temporal lobe epilepsy—selective amygdalohippocampectomy versus anterior temporal lobectomyChristian Dorfer7. Epilepsy in eloquent cortex: resection versus responsive neurostimulationSaadi Ghatan8. Lesional epilepsy: lesionectomy versus ECoG-guided resectionShimrit Sibony-Uliel and Jonathan Roth9. Insular/perisylvian epilepsy: Open resection versus stereotactic ablation (MR-guided laser ablation/radiofrequency thermocoagulation) versus responsive neurostimulationVincent Joris, Jessica Royer and Alexander G. WeilPart 4: Hypothalamic hamartoma10. Hypothalamic hamartoma—open surgery versus endoscopic surgery versus stereotactic radiosurgery versus stereotactic ablation (MR-guided laser ablation/Radiofrequency ablation) versus MRFUSSantiago Candela-Canto, Roberto Martınez Alvarez and Jose Hinojosa Mena-BernalPart 5: Tuberous sclerosis complex11. Resective surgery in tuberous sclerosis complex-related epilepsy: tuberectomy and tuberectomy plusShuli Liang, Zhirong Wei, Jiaqi Wang and Feng ZhaiPart 6: Disconnective procedures12. Functional hemispheric surgery—vertical versus lateral approachJia-Shu Chen, H. Westley Phillips and Aria Fallah13. Minimally invasive hemispherotomy—endoscopic, radiofrequency and robotic techniquesPoodipedi Sarat Chandra and Manjari Tripathi14. Lobar/multilobar epilepsy: resection versus disconnectionVejay N. Vakharia and Martin M. Tisdall15. Corpus callosotomy: anterior two-thirds (two-stage) versus complete (one-stage)Meena Vessell and Robert J. BolloPart 7: Neuromodulation16. Temporal lobe epilepsy with preserved function: multiple hippocampal transection versus neuromodulation (deep brain stimulation, responsive neurostimulation)Logan Massman and Sean Lew17. Neuromodulation: comparison of vagus nerve stimulation, deep brain stimulation, and responsive eurostimulationNebras M. Warsi, Hrishikesh Suresh and George M. Ibrahim