Muscarinic Receptor

From Structure to Animal Models

Inbunden, Engelska, 2024

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This second edition volume expands on the previous edition with updated protocols on basic techniques of radioligand binding, allosteric modulation, visualization and antibody use, and autoradiography and non-neuronal acetylcholine detection.

Produktinformation

Utgivningsdatum2024-07-13
Mått178 x 254 x 26 mm
Vikt896 g
FormatInbunden
SpråkEngelska
SerieNeuromethods
Antal sidor358
Upplaga2
FörlagSpringer-Verlag New York Inc.
ISBN9781071640142

Tillhör följande kategorier

Biovetenskap inom Naturvetenskap och teknik

Radioligand Binding at Muscarinic Receptors.- Tissue-Segment Binding Method for Detection of Muscarinic Acetylcholine Receptors in Receptor’s Natural Environment.- Use of Antibodies in the Research on Muscarinic Receptor Subtypes.- Allosteric Modulation of Ligand Binding to Muscarinic Receptors.- Allosteric Modulation of Functional Response of Muscarinic Receptors.- Exploring Muscarinic Acetylcholine Receptor Binding Kinetics with Fluorescence Anisotropy.- MultiBacMam Technology for Studying the Downstream cAMP Signaling Pathway of M2 Muscarinic Acetylcholine Receptor.- Subcellular and Synaptic Distribution of Muscarinic Receptors in Neurons by Confocal and Electron Microscopy.- Investigation of Muscarinic Receptors by Fluorescent Techniques.- Autoradiography Assessment of Muscarinic Receptors in the Central Nervous System with a Special Focus on the Selectivity for M1 and M2 Muscarinic Receptors: Specific Protocol for M1 Muscarinic Receptors Labelling.- Detection of Non-Neuronal Acetylcholine.- Utilization of Superfused Cerebral Slices in Probing muscarinic Receptor Autoregulation of Acetylcholine Release.- Evaluation of Acetylcholine Synthesis and Release in Striatal Cholinergic Interneurons.- Regulation of Heart Contractility by M2 and M3 Muscarinic Receptors: Functional Studies using Muscarinic Receptor Knockout Mouse.- Muscarinic Regulation of Gastrointestinal Motility.- Systems for a Long-Term Record of Animal Activity, Temperature, and Heart Rate Affected by Muscarinic Receptors.