Molecular Biology of Sacchromyces

At a fundamental research level, the yeasts offer opportunities for modelling regulatory and metabolic processes in multicellular eukaryotic organisms.This volume deals with the mulitfunctional chromosome regulatory proteins, topoisomerase and nuclear transport. A combination of biochemical and genetic approaches applied to the yeast translation system is also currently yielding data, while the mating pheromone signal transduction components used by multicellular organisms, including receptors, G proteins, protein kinases and transcription factors. With a well-established history of fermentation studies, yeasts remain the first-choice vehicle for production of heterologous eukaryotic proteins. Interest is diversifying, as an increasing number of non-Saccharomyces species are now being utilized for the production of specific heterologous proteins. Molecular biologists, microbiologists and biochemical geneticists should find this volume a useful update of this area of research.