Metabolome Analyses:

Strategies for Systems Biology

Häftad, Engelska, 2010

Av Seetharaman Vaidyanathan, George G. Harrigan, Royston Goodacre

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Metabolome analysis is now recognized as a crucial component of functional genomic and systems biology investigations. Innovative approaches to the study of metabolic regulation in microbial, plant and animal systems are increasingly facilitating the emergence of systems approaches in biology.

Produktinformation

Utgivningsdatum2010-10-29
Mått155 x 235 x 23 mm
Vikt628 g
FormatHäftad
SpråkEngelska
Antal sidor390
FörlagSpringer-Verlag New York Inc.
ISBN9781441937803

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Klinisk medicin och internmedicin inom Medicin
Analytisk kemi inom Naturvetenskap och teknik
Biovetenskap inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik

Towards Integrative Functional Genomics Using Yeast as a Reference Model.- Metabolomics for the Assessment of Functional Diversity and Quality Traits in Plants.- Metabolomics: A New Approach Towards Identifying Biomarkers and Therapeutic Targets in CNS Disorders.- Comparative Metabolome Profiling Using Two Dimensional Thin Layer Chromatography (2DTLC).- Capillary Electrophoresis and Its Application in Metabolome Analysis.- Metabolite Profiling with GC-MS and LC-MS.- The Application of Electrochemistry to Metabolic Profiling.- Differential Metabolic Profiling for Biomarker Discovery.- NMR-Based Metabonomics in Toxicology Research.- Methodological Issues and Experimental Design Considerations in Metabolic Profile-Based Classifications.- Modelling of Fungal Metabolism.- Detailed Kinetic Models Using Metabolomics Data Sets.- Metabolic Networks.- Metabolic Networks from a Systems Perspective.- Parallel Metabolite and Transcript Profiling.- Fluxome Profiling in Microbes.- Targeted Drug Design and Metabolic Pathway Flux.- Metabonomics in the Pharmaceutical Industry.- How Lipidomic Approaches Will Benefit the Pharmaceutical Industry.- Metabolites and Fungal Virulence.