Laboratory Techniques in Thrombosis — a Manual

• 1 Introduction to laboratory assays in haemostasis and thrombosis.- 2 Good medical laboratory services — guidelines.- 3 Blood collection and sample preparation: pre-analytical variation.- 4 Quality assessment of haemostatic assays and external quality assessment schemes.- 5 Activated partial thromboplastin time (APTT).- 6 Prothrombin time (PT).- 7 Endogenous thrombin potential.- 8 Fibrinogen.- 9 Activated factor VII.- 10 Factor VII activity and antigen.- 11 Factor VIII clotting activity.- 12 Von Willebrand factor.- 13 Antithrombin activity and antigen.- 14 Protein C activity and antigen.- 15 Protein S antigen.- 16 Protein S activity.- 17 Activated protein C (APC) resistance.- 18 Tissue factor pathway inhibitor (TFPI).- 19 Lupus anticoagulant.- 20 Heparin cofactor II.- 21 Fibrinopeptide A (FPA).- 22 Thrombin-antithrombin (TAT) complexes.- 23 Prothrombin fragment F1+2.- 24 Tissue-type plasminogen activator (t-PA) activity.- 25 Tissue-type plasminogen activator antigen (t-PA Ag).- 26 Plasminogen activator inhibitor-1 (PAI-1) antigen.- "10.1007/978-94-011-4722-4_27".- 28 Plasmin inhibitor activity (previously ?2-antiplasmin).- 29 Plasmin-?2-antiplasmin complexes (plasmin-plasmin inhibitor complexes).- 30 Soluble fibrin and degradation products of fibrinogen (FgDP), fibrin (FbDP; D-dimer) and total of FgDP and FbDP (TDP).- 31 Venous occlusion test in fibrinolysis assays.- 32 List of manufacturers.

'The objective towards standardization is largely met, since world experts on each assay collaborated to evaluate and compare the available methodologies and point to the advantages and disadvantages of each one. This book is written for clinical thrombosis and hemostasis laboratorians. Another attractive feature is the degree of expertise recruited to produce these critical summaries of existing methodologies. This book is a long overdue update of the first edition in view of the multitude of newly developed methodologies and the number of manufacturers involved.' Demetra D. Callas, Loyola University Medical Center in Doody Publishing Inc.