Kisspeptin Signaling in Reproductive Biology

Häftad, Engelska, 2015

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Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood. This places kisspeptin neurons in a unique position to be key nodal points and conduits for conveying numerous endogenous and exogenous signals to the reproductive axis.

Produktinformation

Utgivningsdatum2015-05-24
Mått155 x 235 x 37 mm
Vikt794 g
FormatHäftad
SpråkEngelska
Antal sidor514
Upplaga2013
FörlagSpringer-Verlag New York Inc.
ISBN9781489998392

Tillhör följande kategorier

Biovetenskap inom Naturvetenskap och teknik
Medicinsk utrustning och medicinska tekniker inom Medicin
Endokrinologi inom Medicin
Reproduktionsmedicin inom Medicin

Part One: Kisspeptin Signaling in vivo and in vitro.- Kisspeptin: Past, Present and Prologue.- Structure, Synthesis, and Phylogeny of Kisspeptin and its Receptor.- Neuroanatomy of the Kisspeptin Signaling System in Mammals: Comparative and Developmental Aspects.- The Effects of Kisspeptin on Gonadotropin Release in Non-Human Mammals.- Effects of Kisspeptin on Hormone Secretion in Humans.- Kisspeptin Excitation of GnRH Neurons.- Molecular Biology of the Kisspeptin Receptor: Signaling, Function, and Mutations.- Kisspeptin Antagonists.- Kisspeptin and Clinical Disorders.- Beyond the GnRH Axis: Kisspeptin Regulation of the Oxytocin System in Pregnancy and Lactation.- Part Two: Development and Regulation of Kisspeptin Neurons.- The Development of Kisspeptin Circuits in the Mammalian Brain.- Kisspeptin and Puberty in Mammals.- Sex Steroid Regulation of Kisspeptin Circuits.- Kisspeptin and GnRH Pulse Generation.- Interactions between Kisspeptins and Neurokinin B.- Electrophysiology of Kisspeptin Neurons.- Metabolic Regulation of Kisspeptin.- Circadian Regulation of Kisspeptin in Female Reproductive Functioning.- Kisspeptin and Seasonality of Reproduction.- Stress Regulation of Kisspeptin in the Modulation of Reproductive Function.- Effects of Environmental Endocrine Disruptors and Phytoestrogens on the Kisspeptin System.- Model Systems for Studying Kisspeptin Signaling: Mice and Cells.- Index.