Hypervalent Iodine Compounds

Hypervalent iodine reagents - that is, compounds containing an iodine atom which has more than eight electrons in its valence shell - are now commonly used in organic synthesis as efficient multipurpose reagents whose chemical properties are similar to derivatives of heavy metals but without their toxicity and environmental problems. Modern Hypervalent Iodine Chemistry provides a comprehensive overview of the preparation, properties and synthetic applications of this important class of organic reagents. Topics covered include: Historical background and current areas of active research in hypervalent iodine chemistryClassification and nomenclature of iodine compoundsOverview of hypervalent iodine bonding, structure, and reactivityPreparation, properties, and structure of all specific classes of polyvalent iodine compounds, including inorganic iodine(III) derivatives; (difluoroiodo)arenes; (dichloroiodo)arenes; iodosylarenes; [bis(acyloxy)iodo]arenes; organosulfonates; iodine(III) heterocycles; iodonium salts; iodonium ylides; iodonium imides; inorganic iodine(V) derivatives; non-cyclic and pseudocyclic iodylarenes; iodine(V) heterocycles; and iodine(VII) compoundsSynthetic applications of hypervalent iodine(III), iodine(V), and iodine(VII) reagents, including: fluorinations; chlorinations; brominations; iodinations; oxidation of alcohols; oxidative functionalization of carbonyl compounds; oxidation of alkenes and alkynes; oxidative rearrangements and fragmentations; oxidative dearomatization of phenolic substrates; oxidative coupling of aromatic substrates; thiocyanations, azidations, arylselenations, and aryltellurations; aziridinations and amidations; radical reactions; transition metal catalyzed oxidations; reactions of iodonium salts; arylations; alkenylations; reactions of alkynyl(aryl)iodonium salts; alkylations and fluoroalkylations; 2-iodosylbenzoic acid (IBX); and Dess-Martin periodinane (DMP)Recent achievements in catalytic reactions of hypervalent iodineRecyclable polymer-supported and non-polymeric hypervalent iodine reagents“Green” reactions of hypervalent iodine reagents, including solvent-free reactions, reactions in water, and reactions in ionic liquidsPractical applications of polyvalent iodine compounds in medicine and in industry.Modern Hypervalent Iodine Chemistry is an essential reference for researchers and students in academia and industry working in organic and inorganic synthetic chemistry, and will also find a place on the bookshelves of inorganic, organic, physical, medicinal, pharmaceutical, green and biological chemists.