Hyperthermia and Cancer

Häftad, Engelska, 2012

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My aim is to provide oncologists and other physicians with up-to-date information on this modality, which is both new and old, as well as to make available to biologists, physicists and engineers sum maries of currently available information on specific areas of hyperthermic research.

Produktinformation

Utgivningsdatum2012-03-22
Mått152 x 229 x 17 mm
Vikt438 g
FormatHäftad
SpråkEngelska
Antal sidor298
FörlagSpringer-Verlag New York Inc.
ISBN9781468441956

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Onkologi inom Medicin

1. Introduction: Historical and General Comments.- 2. Mammalian Cell Survival Responses after Exposure to Elevated Temperatures.- 2.1. Introduction.- 2.2. Heat Sensitivity of Mammalian Cells: Definition.- 2.3. Assays.- 2.4. Survival of Cells Exposed to Single Heat Treatments.- 2.5. Modifications of Heat Responses.- 2.6. Survival of Cells Exposed to Multiple Heat Treatments.- 2.7. Summation.- 3. Thermal Enhancement of the Actions of Anticancer Agents.- 3.1. Introduction.- 3.2. Thermal Enhancement of Radiation Sensitivity.- 3.3. Enhancement by Hyperthermia of Drug Cytotoxicity.- 3.4. Summary.- 4. Mechanisms of Heat Action.- 4.1. Introduction.- 4.2. Heat Death of Cells.- 4.3. Heat-Enhanced X-Ray Cytotoxicity.- 4.4. Drug Cytotoxicities at Elevated Temperatures.- 4.5. Summary.- 5. Responses of Murine Tumors and Normal Tissues.- 5.1. Introduction.- 5.2. Responses of Murine Tumors to Hyperthermia Alone.- 5.3. Normal Tissue Responses to Heat.- 5.4. Responses of Tumor and Normal Tissue to Combinations of Heat and X-Ray.- 5.5. Responses of Tumors to Combinations of Heat and Drugs.- 5.6. Do Tumor Cells Die in the Same Manner In Vivo as They Do In Vitro?.- 5.7. Summary.- 6. Technical Aspects of Hyperthermia.- 6.1. Introduction.- 6.2. Localized Heating.- 6.3. Regional Heating.- 6.4. Whole-Body Heating.- 6.5. Possible Adverse Aspects of Heating.- 6.6. Measurement of Temperatures.- 6.7. Summary.- 7. Effects of Hyperthermia Against Spontaneous Cancers.- 7.1. Introduction.- 7.2. Historical Background.- 7.3. Cancers in Out-Bred Animal Populations.- 7.4. Human Cancers: Heat Alone.- 7.5. Human Cancer: Heat Plus Irradiation.- 7.6. Human Cancers: Heat Plus Drugs.- 7.7. Conclusion.- 7.8. Summary.- References.