Human Microbiome in Health and Disease - Part A

Dr Bhabatosh Das is an Associate Professor in Translational Health Science and Technology Institute, an autonomous institute of the Department of Biotechnology, Government of India. He received his MSc degree (2000) from Visva-Bharati University, MTech degree (2002) from IIT-Kharagpur and PhD (2008) from IICB-Kolkata. He moved to France for his postdoctoral training and joined I2BC, France. Dr. Das is recipient of two international fellowships (i) CNRS, Govt. of France (ii) JSPS, Govt. of Japan and three national fellowships (i) IIT (ii) ICMR (iii) CSIR, Govt. of India. He has published 71 research articles 12 book chapters and received more than 2150 citations. Currently, he is Adjunct Visiting Faculty at MAHE-Manipal; Visiting Faculty at NIPER-Guwahati; Adjunct Faculty at RCB-Faridabad; Guest Lecturer at AIIMS-New Delhi. Dr. Das is Editorial Board Member in (i) Microbial Ecology (Springer group) (ii) Gut Microbiome (Cambridge University Press) and (iii) Current Indian Science (Bentham Science). He is guest associate editor in (i) Frontiers in Microbiology (ii) Frontiers in Genetics and (iii) Progress in Molecular Biology and Translational Research. He is a member in (i) GTFCC, WHO (ii) The Nutrition Society, London, UK and (iii) American Society for Microbiology, USA (Former). His current research focuses is Human microbiome and Bacterial antimicrobial resistance. Prof. Vijai Singh is currently serving as Head of the Department of Biosciences, School of Science and Dean (Research & Innovation) at Indrashil University, Rajpur, Mehsana, India. Prior to this, he held the position of Associate Professor in the same department at Indrashil University. He has also served as Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, and in the Department of Biotechnology at the Invertis University, Bareilly, India. Earlier of his career, Prof. Singh worked as a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and at the School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He earned his Ph.D. in Biotechnology in 2009 from the ICAR-National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India. His doctoral research focused on the development of molecular and immunoassays for the diagnosis of Aeromonas hydrophila. Prof. Singh’s research interests lies in the design and construction of novel biosynthetic pathways for production of medically and industrially important biomolecules. His laboratory is also actively engaged in developing CRISPR-Cas systems for gene knock out, knock in, gene regulation and diagnostic. With over 15 years of research and teaching experience, his areas of expertise include synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has an extensive academic record, with over 110 articles, 89 book chapters, 26 books and 3 patents to his credits. Prof. Singh has received number of prestigious awards, including the Bioclues Innovation, Research and Development Award (2023) from the BIOCLUES Society, the Vice Chancellor's Best Research Award (2023) from Indrashil University, and the Agathiyar Chemical Biology Award (2023) from the Society of Chemical and Synthetic Biology. At Indrashil University, he currently serves as chairman of the Board of Study, and is a member of the Academic Council of Indrashil University. He also holds the position of the Member Secretary of the Institutional Biosafety Committee (IBSC) at the university. Dr. Singh is actively involved in national and international scientific advisory roles.

• PrefaceBhabatosh Das and Vijai Singh1. An introduction to human microbiomeBhabatosh Das2. Emerging tools for understanding the human microbiomeTarini Shankar Ghosh and Mrinmoy Das3. Structure, functions, and diversity of the healthy human microbiomeTaruna Ahrodia, Santanu Das, Susmita Bakshi and Bhabatosh Das4. An overview of cancer and the human microbiomeSoumendu Mahapatra, Smrutishree Mohanty, Rasmita Mishra and Punit Prasad5. Gut microbiota in gastrointestinal diseasesGargi Bhattacherjee, Khushal Khambhati, Nisarg Gohil, Priyanka Singh, Jigresh Gohil, Bijun Snehi, Rupesh Maurya, Dinh-Toi Chu, Suresh Ramakrishna and Vijai Singh6. Gut dysbiosis and metabolic diseasesPurbita Bandopadhyay and Dipyaman Ganguly7. Gut microbiome and type 2 diabetesSweta Patel, Sriram Seshadri and Sarat Dalai8. Gut microbiome and non-alcoholic fatty liver diseaseAyushi Purohit, Md Jahangir Alam, Bharti Kandiyal, Shalimar, Bhabatosh Das and Sanjay K. Banerjee9. Hepatic drug metabolism and gut microbiomeTanshi Mehrotra and Subir Kumar Maulik10. Microbiome-based therapeutics: Opportunity and challengesArchana Pant and Bhabatosh Das